Skip to main content

Table 1 Comparison of the demographic characteristics and hemodynamic parameters between survivors and nonsurvivors

From: Peak oxygen uptake is a strong prognostic predictor for pulmonary hypertension due to left heart disease

 

Nonsurvivors (n = 17)

Survivors (n = 72)

P-value*

Age, years

69 (62.5,74.0)

63 (53.3, 72.0)

0.061

Male, n (%)

6 (35.3)

29 (40.3)

0.705

BMI, kg/m2

26.02 (21.5,27.1)

23.12 (21.1, 27.4)

0.266

WHO-FC, n (%)

0.045

 I–II

1 (5.8)

21 (29.2)

 

 III-IV

16 (94.2)

51 (70.8)

6 MWD, m

280 (187.5, 366.5)

410 (325.0, 453.8)

0.001

NT-pro-BNP, pg/ml

1802 (1032.0, 2736.5)

856 (387.5, 1908.5)

0.006

HFrEF, n (%)

1 (5.8)

3 (4.2)

0.759

HFpEF, n (%)

13 (76.5)

39 (54.2)

0.093

VHD#, n (%)

3 (17.6)

30 (41.7)

0.065

Comorbidities, n (%)

Emphysema

8 (47.1)

26 (36.1)

0.403

AF

4 (23.5)

23 (31.9)

0.497

Hypertension

7 (41.2)

30 (41.7)

0.971

Diabetes

3 (17.6)

12 (16.7)

0.923

Renal insufficiency

5 (29.4)

5 (6.9)

0.008

Medication

Diuretics

17 (100)

68 (94.4)

0.320

Anti-arrhythmias

4 (23.5)

19 (26.4)

0.809

Anti-hypertensive

7 (41.2)

30 (41.7)

0.971

Echocardiography

RATD, cm

4.3 (3.8,5.6)

4.2 (3.8,5.0)

0.381

RVEDTD, cm

3.7 (3.1,4.2)

3.6 (3.0,3.9)

0.440

TAPSE, mm

1.7 (1.6,2.2)

1.8 (1.6,2.1)

0.532

Pulmonary hemodynamics

sPAP, mmHg

64.0 (48.5,92.5)

55.0 (45.0, 67.8)

0.141

dPAP, mmHg

22.0 (15.5,30.0)

18.0 (15.0, 24.0)

0.134

mPAP, mmHg

42.0 (28.0,48.0)

34.0 (28.0, 42.0)

0.139

PAWP, mmHg

18.0 (15.5,20.5)

18.0 (16.0, 22.0)

0.543

PVR, Wood U

4.8 (2.5,6.4)

2.9 (2.0, 4.1)

0.023

DPG, mmHg

2.0 (− 5.0,10.5)

− 1.0 (− 3.0, 3.0)

0.029

TPG, mmHg

17.0 (12.0,32.5)

14.5 (10.0, 20.0)

0.086

CO, L/min

4.7 (4.1,5.6)

5.2 (4.1, 6.0)

0.334

  1. The data are shown as the mean ± SD, n (%) or median (quartile range). BMI, body mass index; WHO-FC, World Health Organization function class; 6MWD, 6-min walk distance; HFrEF, heart failure with reduced ejection fraction; HFpEF, heart failure with preserved ejection fraction; VHD, valvular heart disease; AF, atrial fibrillation; RATD, right atrial transverse dimension; RVEDTD, right ventricular end-diastolic transverse dimension; TAPSE, tricuspid annular plane systolic excursion; sPAP, systolic pulmonary artery pressure; dPAP, diastolic pulmonary artery pressure; mPAP, mean pulmonary artery pressure; PAWP, pulmonary artery wedge pressure; PVR, pulmonary vascular resistance; DPG, diastolic pulmonary pressure gradient; TPG, transpulmonary gradient; CO, cardiac output. * When the Bonferroni method was employed to correct the significance level for 22 comparisons made in this study, the adjusted significant level was 0.002. #VHD included moderate or severe mitral or aortic stenosis or insufficiency