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Table 5 Cumulative risk score for CAD associated five significant GWAS SNPs

From: Analysis of 61 SNPs from the CAD specific genomic loci reveals unique set of SNPs as significant markers in the Southern Indian population of Hyderabad

Risk category

Risk score

Cases (%)

Controls (%)

Odds ratio (95% CI)

Z-score

p value

1

0–0.59

29.45

64.17

Reference

2

0.60–1.09

21.57

30.55

1.54 (1.07–2.21)

2.337

0.019

3

1.10–2.09

5.83

3.3

3.85 (1.90–7.81)

3.742

0.0002

4

2.10–6.09

43.15

1.98

47.54 (23.37–96.69)

47.542

 < 0.0001

  1. Bold indicates significant p value/odds ratio