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Table 4 Genotypic association of significant SNPs with coronary artery disease

From: Analysis of 61 SNPs from the CAD specific genomic loci reveals unique set of SNPs as significant markers in the Southern Indian population of Hyderabad

SNP Genotype Frequency OR(95% CI) p value Best model (p value)
Cases n(%) Controls n(%)
rs10455872 AA
AG
GG
193 (57.96)
140 (42.04)
0 (0)
468(98.53)
7(1.47)
0(0)
Reference
48.5(22.3–105)
NA

 < 0.0001
NA
Co dominant (NA)
rs6725887 TT
TC
CC
251 (72.54)
89 (25.72)
6 (1.73)
455(95.99)
19(4.033)
0(0)
Reference
8.49(5.05–14.3)
23.5(1.32–419)

 < 0.0001
0.032
Log-additive (5.21e−21)
rs782590 CC
CT
TT
175 (50.72)
130 (37.68)
40 (11.59)
292(61.99)
149(31.63)
30(6.37)
Reference
1.45(1.08–1.97)
2.22(1.34–3.70)

0.014
0.002
Log-additive (0.0004323)
rs173539 CC
CT
TT
226 (93.77)
12 (4.98)
3 (1.24)
361(97.83)
8(2.17)
0(0)
Reference
2.40(0.96–5.95)
11.2(0.57–217)

0.060
0.111
Log-additive (0.011648)
rs9818870 CC
CT
TT
293 (85.17)
47 (13.66)
4 (1.16)
381(80.04)
85(17.86)
10(2.10)
Reference
0.72(0.49–1.06)
0.52(0.16–1.67)

0.095
0.273
Log-additive (0.2571)
  1. Bold indicates significant p value/odds ratio