Skip to main content

Table 2 Association of significant SNPs with the anatomical categories of coronary artery disease

From: Analysis of 61 SNPs from the CAD specific genomic loci reveals unique set of SNPs as significant markers in the Southern Indian population of Hyderabad

SNP (minor/major allele) MAF in controls N = 480 Insignificant (n = 81) Single vessel disease (n = 98) Double vessel disease (n = 70) Triple vessel disease (n = 66)
MAF OR (95%CI) p value MAF OR (95%CI) p value MAF OR (95%CI) p value MAF OR (95%CI) p value
rs10455872 (G/A) 0.007 0.234 41.2 (17.9–94.4) *1.22e−41 0.177 29.1 (12.6–66.8) *1.22e−30 0.164 26.5 (11.1–63.3) *6.20e−26 0.206 35.0 (14.8–82.7) *4.38e−34
rs6725887 (C/T) 0.020 0.198 12.0 (6.63–21.9) *2.03e−23 0.119 6.58 (3.51–12.3) *3.09e−11 0.123 6.87 (3.48–13.6) *2.56e−10 0.138 7.86 (4.01–15.4) *3.53e−12
rs173539 (T/C)      0.054 5.19 (1.85–14.6) *0.0005 0.042 3.97 (1.17–13.4) 0.017 0.048 4.56 (1.34–15.5) 0.008
rs782590 (T/C)      0.295 1.47 (1.03–2.07) 0.030 0.377 2.12 (1.45–3.09) *7.16e−5    
rs247617 (A/C) 0.259     0.333 1.43 (1.02–1.99) 0.036     0.356 1.58 (1.07–2.32) 0.019
rs2107595 (T/C) 0.325     0.216 0.57 (0.39–0.83) *0.003       
rs3127599 (A/G) 0.205     0.274 1.46 (1.03–2.09) 0.035       
rs9940128 (A/G) 0.440           0.326 0.61 (0.42–0.90) 0.013
rs1083096 (C/G) 0.468           0.364 0.65 (0.44–0.95) 0.024
  1. Bold indicates significant p value (of the odds ratio)
  2. *p value significant after correction for multiple testing