Skip to main content

Table 1 Allelic association of significant SNPs with coronary artery disease

From: Analysis of 61 SNPs from the CAD specific genomic loci reveals unique set of SNPs as significant markers in the Southern Indian population of Hyderabad

SNP ID

Chr/gene location

Alleles

Minor allele frequency (MAF)

χ2

Unadjusted

Adjusted for age and sex

Minor/major

Cases (N = 350)

Controls (N = 480)

 

OR (CI 95%)

p value

OR (CI 95%)

p value

rs10455872*

6/ LPA

G/A

0.210

0.007

194.8

35.9 (16.7–77.2)

2.83e−44

60.0 (26.7–134)

3.54e−23

rs6725887*

2/WDR12

C/T

0.416

0.020

93.5

8.36 (5.16–13.8)

4.04e−22

8.58 (5.09–14.5)

7.22e−16

rs782590*

2/SMEK1

T/C

0.304

0.222

14.2

1.53 (1.23–1.92)

0.0002

1.51 (1.21–1.88)

0.0003

rs173539*

16/HERPUD1-CETP

T/C

0.037

0.011

9.8

3.54 (1.53–8.21)

0.002

2.86 (1.27–6.45)

0.011

rs9818870

3/MRAS

T/C

0.080

0.110

4.2

0.70 (0.50–0.99)

0.041

0.69 (0.49–0.97)

0.032

  1. LPA, lipoprtein A; WDR12, WD repeat domian12; SMEK1, serine/threonine protein phosphatase/suppressor of mek1; HERPUD1-CETP, homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1-cholesteryl ester transfer protein; MRAS, muscle RAS oncogene homolog
  2. *SNP significant after correction for multiple testing
Back to article page

BMC Cardiovascular Disorders

ISSN: 1471-2261

Contact us