Table 1 Characteristics of study patients by NPAR tertiles
Characteristics | Tertile 1 (n = 266) < 21.58 | Tertile 2 (n = 266) ≥ 21.58, < 26.77 | Tertile 3 (n = 266) ≥ 26.77 | p value |
|---|---|---|---|---|
Age (years) | 67.50 (57.00–77.75) | 69.00 (58.00–79.00) | 73.00 (63.00–80.00) | 0.001 |
Male, n (%) | 179 (67.29%) | 165 (62.03%) | 160 (60.15%) | 0.209 |
Race, n (%) | 0.032 | |||
White | 179 (67.29%) | 160 (60.15%) | 179 (67.29%) | |
Black | 21 (7.89%) | 17 (6.39%) | 8 (3.01%) | |
Other | 66 (24.81%) | 89 (33.46%) | 79 (29.70%) | |
Heart rate (beats/minute) | 95.77 ± 25.54 | 101.57 ± 26.39 | 105.51 ± 24.40 | < 0.001 |
MBP (mmHg) | 73.15 ± 34.18 | 67.20 ± 28.90 | 62.95 ± 29.72 | < 0.001 |
Respiratory rate (beats/minute) | 24.24 ± 8.82 | 24.33 ± 9.81 | 25.47 ± 9.94 | 0.240 |
Weight (kg) | 81.94 ± 19.31 | 79.13 ± 19.65 | 77.97 ± 19.72 | 0.017 |
CAD | 192 (72.18%) | 207 (77.82%) | 146 (54.89%) | < 0.001 |
Prior MI | 15 (5.64%) | 18 (6.77%) | 13 (4.89%) | 0.645 |
AF | 67 (25.19%) | 80 (30.08%) | 100 (37.59%) | 0.008 |
Hypertension | 136 (51.13%) | 118 (44.36%) | 91 (34.21%) | < 0.001 |
Diabetes | 75 (28.20%) | 76 (28.57%) | 80 (30.08%) | 0.880 |
CHF | 105 (39.47%) | 136 (51.13%) | 135 (50.75%) | 0.009 |
CKD | 29 (10.90%) | 37 (13.91%) | 42 (15.79%) | 0.251 |
Stroke | 6 (2.26%) | 10 (3.76%) | 14 (5.26%) | 0.190 |
COPD | 4 (1.50%) | 2 (0.75%) | 8 (3.01%) | 0.131 |
PTCA/PCI | 187 (70.30%) | 173 (65.04%) | 125 (46.99%) | < 0.001 |
Laboratory parameters | ||||
Neutrophil percentage (%) | 71.20 (61.35–78.95) | 84.00 (77.60–88.07) | 86.00 (80.85–89.77) | < 0.001 |
Albumin (g/dL) | 3.80 (3.50–4.10) | 3.50 (3.20–3.70) | 2.70 (2.40–3.00) | < 0.001 |
Hemoglobin (g/dL) | 13.35 (11.90–14.57) | 12.60 (11.10–14.10) | 11.35 (10.10–12.97) | < 0.001 |
WBC (109/L) | 10.30 (7.50–13.80) | 12.50 (9.60–16.70) | 13.70 (10.10–17.50) | < 0.001 |
PT (seconds) | 13.30 (12.50–14.00) | 13.70 (12.90–15.10) | 14.50 (13.30–16.88) | < 0.001 |
Platelet (109/L) | 242.50 (188.25–301.75) | 252.00 (192.25–299.00) | 230.50 (170.25–302.75) | 0.113 |
RDW (%) | 13.60 (13.10–14.50) | 13.70 (13.00–14.50) | 14.20 (13.30–15.60) | < 0.001 |
Potassium (mmol/L) | 4.20 (3.90–4.60) | 4.10 (3.80–4.50) | 4.20 (3.80–4.70) | 0.216 |
Sodium (mmol/L) | 139.00 (137.00–141.00) | 138.00 (135.25–141.00) | 139.00 (134.25–141.00) | 0.036 |
Creatinine (mEq/L) | 1.10 (0.90–1.40) | 1.10 (0.90–1.40) | 1.20 (1.00–1.70) | < 0.001 |
BUN (mg/dL) | 20.00 (15.00–28.00) | 21.00 (15.00–30.25) | 27.00 (18.50–43.50) | < 0.001 |
ALT (U/L) | 30.21 (20.00–62.75) | 37.00 (21.00–68.75) | 42.33 (22.00–79.00) | 0.024 |
AST (U/L) | 52.00 (26.25–124.63) | 74.50 (34.24–174.00) | 77.70 (38.00–196.37) | 0.001 |
CK-peak (U/L) | 743.30 (292.70–1756.00) | 1088.50 (329.25–2427.20) | 702.00 (252.15–1983.00) | 0.052 |
CK-MB-peak (U/L) | 53.00 (14.00–181.00) | 72.00 (13.00–227.50) | 37.00 (11.00–150.00) | 0.092 |
Glucose (mg/dL) | 143.00 (115.25–191.75) | 148.00 (122.25–207.25) | 152.00 (119.25–213.75) | 0.254 |
Scoring systems | ||||
SAPS II | 34.00 (25.00–44.00) | 36.00 (28.00–48.00) | 43.00 (35.00–54.00) | < 0.001 |
SOFA | 3.00 (1.00–2.00) | 4.00 (3.00–5.00) | 6.00 (7.00–10.00) | < 0.001 |
Medication use, n (%) | ||||
Aspirin | 214 (80.45%) | 221 (83.08%) | 172 (64.66%) | < 0.001 |
Clopidogre | 132 (49.62%) | 148 (55.64%) | 117 (43.98%) | 0.027 |
Metoprolol | 209 (78.57%) | 197 (74.06%) | 156 (58.65%) | < 0.001 |
ACEI/ARBs | 156 (58.65%) | 171 (64.29%) | 100 (37.59%) | < 0.001 |
Statin | 201 (75.56%) | 199 (74.81%) | 156 (58.65%) | < 0.001 |
Urine output (ml/24 h) | 2116.00 (1424.00–3074.00) | 1825.00 (1090.00–2718.75) | 1377.50 (812.25–2275.25) | < 0.001 |