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Table 1 Hemodynamic parameters measured at baseline, post dilation, and after ring annuloplasty repair using flexible and rigid rings

From: Ex vivo biomechanical analysis of flexible versus rigid annuloplasty rings in mitral valves using a novel annular dilation system

Hemodynamic parameters

Baseline

Post dilation

Flexible annuloplasty ring

Rigid annuloplasty ring

P value baseline versus post dilation

P value post dilation versus flexible annuloplasty ring

P value post dilation versus rigid annuloplasty ring

Heart rate (bpm)

70 ± 0

70 ± 0

70 ± 0

70 ± 0

–

–

–

Pump stroke volume (mL)

101.0 ± 0.1

109.9 ± 0.1

109.9 ± 0.0

109.9 ± 0.1

0.87

0.81

0.61

Effective stroke volume (mL)

51.2 ± 6.3

46.1 ± 10.1

46.0 ± 10.0

50.5 ± 7.4

0.09

0.97

0.06

Cardiac output (L/min)

3.6 ± 0.4

3.2 ± 0.7

3.2 ± 0.7

3.5 ± 0.5

0.09

0.97

0.06

Mean aortic pressure (mmHg)

101.3 ± 2.6

96.7 ± 14.0

99.0 ± 14.1

101.0 ± 13.0

0.53

0.05

0.03

Systolic aortic pressure (mmHg)

118.5 ± 2.7

112.8 ± 15.5

115.3 ± 15.7

117.9 ± 13.6

0.48

0.18

0.04

Diastolic aortic pressure (mmHg)

85.1 ± 3.0

81.5 ± 12.7

83.4 ± 12.8

85.2 ± 12.1

0.60

0.07

0.03

Ventricular mean pressure (mmHg)

43.6 ± 5.5

43.3 ± 5.7

44.3 ± 6.4

45.0 ± 6.5

0.94

0.15

0.04

Atrial mean pressure (mmHg)

8.6 ± 7.8

11.1 ± 0.8

11.0 ± 2.2

11.3 ± 2.4

0.55

0.89

0.86

Mitral valve mean gradient (mmHg)

1.1 ± 1.3

0.8 ± 0.4

1.7 ± 0.4

1.3 ± 0.3

0.74

0.004

0.21

Mitral forward flow time (s)

0.6 ± 0.0

0.5 ± 0.0

0.6 ± 0.0

0.6 ± 0.0

0.18

0.08

0.12

Mitral forward volume (mL)

59.9 ± 10.0

59.6 ± 9.5

58.3 ± 9.3

61.4 ± 8.2

0.78

0.52

0.13

Mitral closing volume (mL)

− 7.2 ± 4.8

− 11.8 ± 1.9

− 10.7 ± 0.6

− 10.5 ± 1.3

0.17

0.25

0.06

Mitral regurgitant fraction (%)

13.9 ± 4.4

23.2 ± 5.5

21.6 ± 6.1

17.8 ± 2.8

0.14

0.32

0.05

Transmitral forward energy loss (mJ)

− 2.8 ± 16.2

− 14.0 ± 7.3

− 5.5 ± 10.1

− 11.0 ± 7.7

0.12

0.04

0.64

Transmitral closing energy loss (mJ)

31.3 ± 27.3

51.4 ± 8.7

58.1 ± 14.4

56.6 ± 14.8

0.19

0.54

0.58

Transmitral leakage energy loss (mJ)

20.1 ± 11.0

25.3 ± 9.1

21.3 ± 25.8

7.7 ± 16.5

0.02

0.81

0.24

Transmitral total energy loss (mJ)

48.6 ± 7.0

62.7 ± 8.5

73.9 ± 22.6

53.4 ± 11.2

0.13

0.34

0.28

  1. Data presented as mean ± standard deviation. Values in bold designate statistical significance