Fig. 3

The pathology of the first biopsy via femoral vein shows a large amount of cellulose and blood cells, diagnosed as thrombus (a hematoxylin and eosin, 40 × 10). The pathology of the secondary biopsy through the right internal jugular vein reveals a spindle cell tumor, some areas are rich in spindle cells, with moderate atypia and focal necrosis, and the histology is consistent with intimal sarcoma (b hematoxylin and eosin, 40 × 10). Immunohistochemistry-positive neoplastic cells for PRAME (c 40 × 10)