Construction of genetic classification model for coronary atherosclerosis heart disease using three machine learning methods

Peng, Wenjuan; Sun, Yuan; Zhang, Ling

doi:10.1186/s12872-022-02481-4

Table 2 The information of 33 hub genes identified by weighed gene co-expression network analysis

From: Construction of genetic classification model for coronary atherosclerosis heart disease using three machine learning methods

Gene symbol	Module	GS	P.GS	MM	P.MM
ZAP70	Black	− 0.273	1.11E−09	0.810	8.54E−113
HTR4	Blue	0.224	6.76E−07	0.853	6.29E−137
CA12	Blue	0.203	7.61E−06	0.845	7.38E−132
KLK2	Blue	0.209	4.07E−06	0.821	3.04E−118
DERL1	Brown	0.232	2.79E−07	0.807	3.38E−111
NFIL3	Green	0.211	3.01E−06	0.839	2.35E−128
BCL6	Green	0.240	1.03E−07	0.842	5.09E−130
FPR1	Green	0.220	1.09E−06	0.802	4.99E−109
ACSL1	Green	0.213	2.63E−06	0.834	2.15E−125
CSF3R	Green	0.210	3.35E−06	0.815	3.28E−115
C5AR1	Green	0.238	1.35E−07	0.801	2.41E−108
NCF2	Green	0.271	1.58E−09	0.844	2.57E−131
CNGB1	Turquoise	− 0.298	2.63E−11	0.877	4.70E−154
DDC	Turquoise	− 0.334	5.92E−14	0.811	1.47E−113
CAMK2B	Turquoise	− 0.339	2.17E−14	0.866	9.86E−146
HCN2	Turquoise	− 0.222	8.74E−07	0.808	5.01E−112
MUC13	Turquoise	− 0.436	1.21E−23	0.852	1.03E−136
KISS1	Turquoise	− 0.383	3.52E−18	0.841	1.55E−129
JPH2	Turquoise	− 0.254	1.64E−08	0.808	4.63E−112
ADRA2C	Turquoise	− 0.214	2.16E−06	0.810	9.52E−113
MTF2	Turquoise	0.233	2.49E−07	− 0.872	9.16E−151
LHX5	Turquoise	− 0.237	1.55E−07	0.827	8.63E−122
EMID1	Turquoise	− 0.239	1.23E−07	0.811	3.21E−113
HSD17B14	Turquoise	− 0.285	2.14E−10	0.816	7.91E−116
RTEL1	Turquoise	− 0.223	7.75E−07	0.813	3.04E−114
PRKCD	Yellow	0.296	3.58E−11	0.841	2.05E−129
LILRA2	Yellow	0.254	1.56E−08	0.834	1.42E−125
PILRA	Yellow	0.222	9.12E−07	0.870	3.90E−149
PGD	Yellow	0.259	8.04E−09	0.808	4.25E−112
APLP2	Yellow	0.205	5.73E−06	0.816	7.83E−116
LYN	Yellow	0.203	7.19E−06	0.822	4.14E−119
HCK	Yellow	0.243	6.66E−08	0.882	3.17E−158
TYROBP	Yellow	0.252	2.25E−08	0.875	2.03E−152

GS, gene significance with coronary atherosclerosis heart disease; P.GS, P value for gene significance with coronary atherosclerosis heart disease; MM, module membership; P.MM, P value for module membership

Back to article page

ISSN: 1471-2261

Contact us

Submission enquiries: bmccardiovasculardisorders@biomedcentral.com
General enquiries: ORSupport@springernature.com

BMC Cardiovascular Disorders

Contact us