Items | Bleeding | Univariate | Multivariate | |||
---|---|---|---|---|---|---|
No (%) | Yes (%) | P value | OR (95% CI) | P value | OR (95% CI) | |
Age |  |  | 0.273 |  | – |  |
  > 75 years | 226 (97.8) | 5 (2.2) |  | 1.878 (0.608–5.798) |  | – |
  ≤ 75 years | 679 (98.8) | 8 (1.2) |  | Reference |  | – |
BMI |  |  | 0.997 |  | – |  |
  > 28 kg/m2 | 87 (100.0) | 0 (0.0) |  | – |  | – |
  ≤ 28 kg/m2 | 760 (98.3) | 13 (1.7) |  | – |  | – |
History of diabetes mellitus | Â | Â | 0.005 | Â | 0.007 | Â |
 Yes | 266 (96.7) | 9 (3.3) |  | 5.405 (1.650–17.704) |  | 5.227 (1.562–17.495) |
 No | 639 (99.4) | 4 (0.6) |  | Reference |  | Reference |
History of allergy |  |  | 0.654 |  | – |  |
 Yes | 103 (98.1) | 2 (1.9) |  | 1.416 (0.309–6.476) |  | – |
 No | 802 (98.6) | 11 (1.4) |  | Reference |  | – |
History of cardiac surgery |  |  | 0.984 |  | – |  |
 Yes | 71 (98.6) | 1 (1.4) |  | 0.979 (0.125–7.637) |  | – |
 No | 834 (98.6) | 12 (1.4) |  | Reference |  | – |
History of renal function impairment |  |  | 0.328 |  | – |  |
 Yes | 26 (96.3) | 1 (3.7) |  | 2.817 (0.353–22.482) |  | – |
 No | 879 (98.7) | 12 (1.3) |  | Reference |  | – |
History of critical respiratory disease |  |  | 0.998 |  | – |  |
 Yes | 20 (100.0) | 0 (0.0) |  | – |  | – |
 No | 885 (98.6) | 13 (1.4) |  | – |  | – |
Clinical presentation-UA | Â | Â | 0.048 | Â | 0.103 | Â |
 Yes | 359 (99.7) | 1 (0.3) |  | 0.127 (0.016–0.979) |  | 0.178 (0.022–1.420) |
 No | 546 (97.8) | 12 (2.2) |  | Reference |  | Reference |
Clinical presentation-STEMI |  |  | 0.182 |  | – |  |
 Yes | 322 (97.9) | 7 (2.1) |  | 2.112 (0.704–6.339) |  | – |
 No | 583 (99.0) | 6 (1.0) |  | Reference |  | – |
Clinical presentation-NSTMI |  |  | 0.889 |  | – |  |
 Yes | 127 (98.4) | 2 (1.6) |  | 1.114 (0.244–5.084) |  | – |
 No | 778 (98.6) | 11 (1.4) |  | Reference |  | – |
Clinical presentation-SCAD |  |  | 0.164 |  | – |  |
 Yes | 96 (97.0) | 3 (3.0) |  | 2.528 (0.684–9.346) |  | – |
 No | 809 (98.8) | 10 (1.2) |  | Reference |  | – |
CRUSADE risk stratification | Â | Â | 0.003 | Â | 0.016 | Â |
 High risk | 239 (96.4) | 9 (3.6) |  | 6.129 (1.870–20.087) |  | 4.475 (1.323–15.134) |
 No high risk | 651 (99.4) | 4 (0.6) |  | Reference |  | Reference |
Operative timing |  |  | 0.090 |  | – |  |
 Elective operation | 564 (99.1) | 5 (0.9) |  | 0.378 (0.123–1.164) |  | – |
 Emergency operation | 341 (97.7) | 8 (2.3) |  | Reference |  | – |
Types of coronary interventional therapy |  |  | 0.658 |  | – |  |
 Stent implantation | 860 (98.6) | 12 (1.4) |  | 0.628 (0.080–4.936) |  | – |
 Others | 45 (97.8) | 1 (2.2) |  | Reference |  | – |
Types of stents |  |  | 0.999 |  | – |  |
 Drug stent | 848 (98.6) | 12 (1.4) |  | – |  | – |
 Others | 15 (100.0) | 0 (0.0) |  | – |  | – |
Arterial access |  |  | 0.997 |  | – |  |
 Radial artery | 835 (98.5) | 13 (1.5) |  | – |  | – |
 Others | 70 (100.0) | 0 (0.0) |  | – |  | – |
Culprit vessel |  |  | 0.559 |  | – |  |
 Multiple | 201 (99.0) | 2 (1.0) |  | 0.637 (0.140–2.896) |  | – |
 Single | 704 (98.5) | 11 (1.5) |  | Reference |  | – |
Administration of bivalirudin-preoperative or intraoperative |  |  | 0.401 |  | – |  |
 Yes | 30 (96.8) | 1 (3.2) |  | 2.431 (0.306–19.304) |  | – |
 No | 875 (98.6) | 12 (1.4) |  | Reference |  | – |
Administration of bivalirudin-postoperative ≤ 4 h |  |  | 0.126 |  | – |  |
 Yes | 770 (98.8) | 9 (1.2) |  | 0.394 (0.120–1.299) |  | – |
 No | 135 (97.1) | 4 (2.9) |  | Reference |  | – |
Administration of bivalirudin-postoperative > 4 h |  |  | 0.215 |  | – |  |
 Yes | 105 (97.2) | 3 (2.8) |  | 2.286 (0.619–8.439) |  | – |
 No | 800 (98.8) | 10 (1.2) |  | Reference |  | – |
Combined with GP IIb/IIIa inhibitors |  |  | 0.326 |  | – |  |
 Yes | 652 (98.3) | 11 (1.7) |  | 2.134 (0.470–9.696) |  | – |
 No | 253 (99.2) | 2 (0.8) |  | Reference |  | – |
TIMI flow grade (pre-procedure) |  |  | 0.173 |  | – |  |
 2–3 | 518 (98.1) | 10 (1.9) |  | 2.465 (0.674–9.016) |  | – |
 0–1 | 383 (99.2) | 3 (0.8) |  | Reference |  | – |
TIMI flow grade (post-procedure) | Â | Â | 0.033 | Â | 0.069 | Â |
 2–3 | 897 (98.7) | 12 (1.3) |  | 0.094 (0.011–0.821) |  | 0.105 (0.009–1.187) |
 0–1 | 7 (87.5) | 1 (12.5) |  | Reference |  | Reference |