Skip to main content
Fig. 3 | BMC Cardiovascular Disorders

Fig. 3

From: MiR-138-5p targets RUNX2 to inhibit osteogenic differentiation of aortic valve interstitial cells via Wnt/β-catenin signaling pathway

Fig. 3

MiR-138-5p inhibits osteogenic differentiation of hAVICs by decreasing RUNX2. A RT-qPCR for detecting RUNX2 expression in hAVICs; B Evaluation of osteogenesis of hAVICs by ALP staining; C ALP activity of hAVICs; D Alizarin red staining for confirming calcification of hAVICs; E Western blot-based detection of RUNX2, OPN and ALP proteins in hAVICs. **P < 0.01 versus Calcified-NC group; ##P < 0.01 versus Calcified-mi-miR-138-5p group

Back to article page

BMC Cardiovascular Disorders

ISSN: 1471-2261

Contact us