Clinical and psychological factors in coronary heart disease patients with statin associated muscle side-effects

Table 3 Muscle symptom presentation in patients with confirmed SAMS^a and refuted SAMS in MUSE trial

	Confirmed SAMS (n = 20)	Refuted SAMS (n = 51)	p-value
Baseline muscle symptom intensity (VAS-score^b), mean (SD)	4.5 (2.7)	4.7 (2.4)	0.84
Baseline muscle symptom characteristics^c
Sensory dimension, mean (SD)	10.5 (5.7)	11.5 (7.1)	0.62
Affective dimension, mean (SD)	2.9 (2.1)	2.5 (2.6)	0.58
Total sum-score, mean (SD)	13.5 (7.1)	13.8 (9.2)	0.90
Muscle symptom location on statin treatment^d
Bilateral muscle pain lower extremities, n (%)	15 (75)	21 (41)	0.01
Bilateral muscle pain upper extremities, n (%)	11 (55)	18 (35)	0.13
Bilateral muscle pain both regions, n (%)	8 (40)	9 (18)	0.05

SD, standard deviations, ^aSAMS, statin associated muscle symptoms, ^bVAS-score, Visual Analog Scale, ^cMuscle symptom characteristics measured with Short-form McGill Pain Questionnaire, ^dMuscle symptom location measured with Margolis pain drawings

ISSN: 1471-2261