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Table 1 Study participant characteristics at Enrollment into a Mixed HIV-Serostatus Cohort in Uganda

From: Prevalence and correlates of carotid plaque in a mixed HIV-serostatus cohort in Uganda

Characteristic

Overall (n = 309)

HIV-negative (n = 154)

PLWH (n = 155)

P-value*

Age, years (mean, SD)

51.4 (7.2)

51.5 (7.7)

51.2 (6.6)

0.695

Female (n, %)

151 (48.9)

77 (50.0)

74 (47.7)

0.691

Smoking status (n, %)

   

 < 0.001

 Never-smoker

163 (52.8)

72 (46.8)

91 (58.7)

 

 Former smoker

105 (34.0)

50 (32.5)

55 (35.5)

 

 Current smoker

41 (13.3)

32 (20.8)

9 (5.8)

 

Physical activityβ (n, %)

   

0.003

 Low intensity

16 (5.2)

3 (2.0)

13 (8.4)

 

 Moderate intensity

42 (13.6)

15 (9.7)

27 (17.4)

 

 Vigorous intensity

251 (81.2)

136 (88.3)

115 (74.2)

 

Body mass index (n, %)

   

0.056

 Underweight (< 18.5 kg/m2)

40 (12.9)

27 (17.5)

13 (8.4)

 

 Normal (18.5- ≤ 25 kg/m2)

189 (61.2)

90 (58.4)

99 (63.9)

 

 Overweight/Obese (> 25 kg/m2)

80 (25.9)

37 (24.0)

43 (27.7)

 

Hemoglobin A1c, % (mean, SD)

5.5 (1.0)

5.6 (0.8)

5.4 (1.1)

0.287

Total cholesterol, mg/dL (mean, SD)

160.1 (35.9)

159.5 (33.2)

160.6 (38.4)

0.788

Mean systolic BP, mmHg (median, IQR)

114.5 (105.5, 126.5)

117.5 (108, 131.5)

112.5 (100, 120)

0.015

Mean diastolic BP, mmHg (median, IQR)

73 (66, 81.5)

77 (68.5, 83.5)

69 (63.5, 79.0)

 < 0.001

Virologic suppressionΩ at enrollment (n, %)

N/A

N/A

150 (97.4)

 

Nadir CD4 count, cells/µ (median, IQR)

N/A

N/A

118 (74, 183)

 

CD4 count at enrollment, cells/µ (median, IQR)

N/A

N/A

433 (336, 559)

 

ART Regimen (n, %)

N/A

N/A

  

 NVP-based

N/A

N/A

99 (63.9)

 

 EFV-based

N/A

N/A

42 (27.1)

 

 PI-based

N/A

N/A

14 (9.0)

 
  1. IQR interquartile range; SD standard deviation; ART regimen antiretroviral therapy regimen; AZT zidovudine; 3TC lamivudine; NVP nevirapine; EFV efavirenze; TDF tenofovir; PI protease inhibitor; N/A not applicable
  2. *P-values comparing the PLWH with the HIV-uninfected were calculated using chi-squared testing for categorical variables and t tests for normally distributed continuous variables
  3. βPhysical activity categories were determined by the International Physical Activity Questionnaire (IPAQ) scoring protocol
  4. ΩVirologic suppression defined as having less than 1000 copies of HIV per milliliter of blood
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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