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Table 2 Incidence of atrial fibrillation in relation to anthropometric measures in (A) men, (B) women

From: Anthropometric measures and the risk of developing atrial fibrillation: a Swedish Cohort Study

Quartiles Q1 Q2 Q3 Q4 Q4 vs. Q1 p-value
(A)      
 BMI (n) 2460 2474 2471 2478  
 AF/1000a 9.52 10.7 11.3 16.1  
 BMI (median, kg/m2) 22.5 24.9 26.9 29.9  
 HR-1b 1 1.04 (0.91–1.18) 1.11 (0.98–1.26) 1.66 (1.47–1.88) < 0.001
 HR-2c 1 1.05 (0.92–1.19) 1.12 (0.98–1.28) 1.61 (1.42–1.83) < 0.001
 HR-3d 1 1.05 (0.92–1.19) 1.12 (0.98–1.28) 1.62 (1.42–1.84) < 0.001
 WC (n) 2340 2492 2310 2741  
 AF/1000a 9.03 10.6 11.8 15.8  
 WC (median, cm) 82 90 95 104  
 HR-1b 1 1.13 (0.99–1.28) 1.24 (1.09–1.42) 1.72 (1.52–1.95) < 0.001
 HR-2c 1 1.14 (1.00–1.31) 1.25 (1.09–1.43) 1.68 (1.48–1.92) < 0.001
 HR-3d 1 1.14 (1.00–1.30) 1.23 (1.08–1.41) 1.67 (1.46–1.90) < 0.001
 WHR (n) 2457 2457 2482 2487  
 AF/1000a 11.0 11.4 11.5 13.5  
 WHR (median) 0.88 0.92 0.96 1.01  
 HR-1b 1 1.06 (0.94–1.20) 1.09 (0.96–1.23) 1.39 (1.23–1.57) < 0.001
 HR-2c 1 1.05 (0.93–1.19) 1.04 (0.92–1.18) 1.30 (1.15–1.47) < 0.001
 HR-3d 1 1.05 (0.93–1.19) 1.04 (0.92–1.18) 1.3 (1.14–1.47) < 0.001
 WHtR (n) 2467 2455 2483 2478  
 AF/1000a 9.83 10.7 11.6 15.6  
 WHtR (median) 0.47 0.51 0.54 0.59  
 HR-1b 1 1.02 (0.89–1.15) 1.07 (0.94–1.21) 1.45 (1.28–1.64) < 0.001
 HR-2c 1 1.00 (0.88–1.14) 1.05 (0.92–1.19) 1.35 (1.19–1.54) < 0.001
 HR-3d 1 1.00 (0.88–1.14) 1.05 (0.92–1.19) 1.37 (1.20–1.56) < 0.001
 BF % (n) 1912 2339 3158 2474  
 AF/1000a 10.9 10.3 12.0 14.0  
 BF % (median) 15 18 21 26  
 HR-1b 1 0.91 (0.79–1.04) 1.07 (0.94–1.21) 1.27 (1.12–1.44) < 0.001
 HR-2c 1 0.90 (0.79–1.04) 1.04 (0.92–1.19) 1.22 (1.07–1.39) < 0.005
 HR-3d 1 0.90 (0.79–1.04) 1.04 (0.92–1.18) 1.21 (1.06–1.39) < 0.005
 Weight (n) 2162 2741 2477 2503  
 AF/1000a 8.49 10.7 12.2 15.7  
 Weight (median, kg) 68 77 84 95  
 HR-1b 1 1.23 (1.08–1.42) 1.46 (1.28–1.68) 2.06 (1.80–2.35) < 0.001
 HR-2c 1 1.26 (1.10–1.44) 1.49 (1.29–1.71) 2.06 (1.80–2.36) < 0.001
 HR-3d 1 1.25 (1.08–1.43) 1.46 (1.27–1.68) 2.02 (1.76–2.32) < 0.001
 Height (n) 2204 2179 2822 2678  
 AF/1000a 10.4 11.1 12.2 13.1  
 Height (median, cm) 168 174 178 184  
 HR-1b 1 1.16 (1.01–1.33) 1.33 (1.17–1.51) 1.62 (1.43–1.84) < 0.001
 HR-2c 1 1.16 (1.02–1.33) 1.38 (1.21–1.56) 1.69 (1.49–1.92) < 0.001
 HR-3d 1 1.16 (1.01–1.32) 1.36 (1.2–1.54) 1.66 (1.46–1.89) < 0.001
(B)      
 BMI (n) 4016 4023 4008 4031  
 AF/1000a 4.82 5.87 7.44 10.00  
 BMI (median, kg/m2) 21.1 23.5 26.0 30.1  
 HR-1b 1 1.08 (0.95–1.24) 1.22 (1.08–1.40) 1.61 (1.42–1.82) < 0.001
 HR-2c 1 1.09 (0.95–1.25) 1.22 (1.07–1.39) 1.51 (1.32–1.72) < 0.001
 HR-3d 1 1.09 (0.96–1.25) 1.22 (1.07–1.40) 1.52 (1.33–1.73) < 0.001
 WC (n) 3500 4231 3994 4353  
AF/1000a 4.58 5.77 7.04 10.3  
 WC (median. cm) 67 72 79 89  
 HR-1b 1 1.13 (0.98–1.29) 1.29 (1.12–1.48) 1.71 (1.50–1.95) < 0.001
 HR-2c 1 1.13 (0.98–1.30) 1.30 (1.13–1.49) 1.62 (1.42–1.86) < 0.001
 HR-3d 1 1.13 (0.98–1.30) 1.31 (1.14–1.50) 1.63 (1.422–1.88) < 0.001
 WHR (n) 3991 4034 3999 4054  
 AF/1000a 6.31 6.32 6.69 8.71  
 WHR (median) 0.74 0.77 0.80 0.85  
 HR-1b 1 1.05 (0.93–1.19) 1.05 (0.93–1.19) 1.33 (1.19–1.50) < 0.001
 HR-2c 1 1.05(0.93–1.18) 1.03 (0.91–1.16) 1.24 (1.09–1.40) 0.001
 HR-3d 1 1.05 (0.93–1.19) 1.03 (0.91–1.12) 1.24 (1.09–1.40) 0.001
 WHtR (n) 4006 4032 4018 4022  
 AF/1000a 4.57 6.06 7.49 10.1  
 WHtR (median) 0.41 0.45 0.48 0.55  
 HR-1b 1 1.11 (0.97–1.27) 1.23 (1.08–1.40) 1.51 (1.33–1.71) < 0.001
 HR-2c 1 1.10 (0.96–1.26) 1.21 (1.06–1.38) 1.38 (1.20–1.58) < 0.001
 HR-3d 1 1.10 (0.96–1.26) 1.22 (1.06–1.39) 1.39 (1.21–1.59) < 0.001
 BF % (n) 3113 4493 3711 4761  
 AF/1000a 4.55 5.76 6.88 9.98  
 BF % (median) 24 29 32 36  
 HR-1b 1 1.11 (0.96–1.28) 1.12 (0.966–1.29) 1.53 (1.34–1.75) < 0.001
 HR-2c 1 1.14 (0.98–1.32) 1.13 (0.97–1.31) 1.44 (1.25–1.66) < 0.001
 HR-3d 1 1.14 (0.98–1.32) 1.13 (0.97–1.31) 1.45 (1.26–1.67) < 0.001
 Weight (n) 3744 3812 4255 4267  
 AF/1000a 4.92 5.52 7.10 10.13  
 Weight (median, kg) 56 63 69 80  
 HR-1b 1 1.12 (0.97–1.28) 1.41 (1.24–1.6) 2.00 (1.77–2.26) < 0.001
 HR-2c 1 1.13 (0.98–1.30) 1.44 (1.26–1.64) 1.93 (1.70–2.20) < 0.001
 HR-3d 1 1.13 (0.98–1.30) 1.44 (1.27–1.65) 1.93 (1.70–2.20) < 0.001
 Height (n) 3920 3992 3915 4251  
 AF/1000a 6.72 6.74 7.02 7.41  
 Height (median, cm) 157 162 165 170  
 HR-1b 1 1.16 (1.03–1.32) 1.37 (1.21–1.55) 1.82 (1.62–2.06) < 0.001
 HR-2c 1 1.19 (1.19–1.06) 1.40 (1.24–1.58) 1.90 (1.68–2.14) < 0.001
 HR-3d 1 1.20 (1.06–1.36) 1.42 (1.26–1.61) 1.93 (1.71–2.18) < 0.001
  1. aMeasured as number of AF per 1000-person years
  2. bCox-regression Hazard Ratio (HR) adjusted for age (95% CI)
  3. cHR-2 adjusted for age, use of antihypertensive medication, lipid-lowering medication, systolic blood pressure, smoking, low physical activity, Apo-A and Apo-B blood levels and diabetes (95% CI)
  4. dHR-3 adjusted for HR-2 plus alcohol consumption, low education, marital status and immigrant status (95% CI)
  5. AF Atrial Fibrillation, BMI body mass index, WC waist circumference, WHR waist-hip ratio, WHtR waist-height ratio, BF % body-fat percentage, CI confidence interval