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Table 5 Subgroup analysis of two kinds of cardioplegia solution according to whether the aortic clamping time more than 120 min

From: Del Nido versus HTK cardioplegia for myocardial protection during adult complex valve surgery: a retrospective study

Outcomes

Aortic Clamping time

 

 ≥ 120 min

 < 120 min

DN(n = 29)

HTK(n = 26)

P-value

DN(n = 44)

HTK(n = 47)

P-value

Aortic clamping time [P50(P25,P75), min]

137(125,160)

146.5(131,164)

0.194

78(63,102)

87(68,99)

0.432

Return to spontaneous rhythm [n(%)]

27(93.1)

11(42.3)

0.000

37(84.1)

27(57.4)

0.005

Dop [P50(P25,P75)]

3(0,3.5)

3(1,3)

0.696

2(1,3)

3(0,4)

0.373

Ne [P50(P25,P75)]

3(1.5,4)

2.5(2,3)

0.620

2(1,3)

3(2,4)

0.025

E [P50(P25,P75)]

2(0,2.5)

2(1,3)

0.437

1(0,2)

1(0,3)

0.233

Postoperative low cardiac output [n(%)]

4(13.8)

6(23.1)

0.373

2(4.5)

6(12.8)

0.166

Postoperative arrhythmia [n(%)]

5(17.2)

9(34.6)

0.140

4(9.1)

10(21.3)

0.107

MV time [P50(P25,P75), hour]

16(11.5,27.5)

19(13.5,27)

0.813

15(10,21.5)

19(13,26)

0.065

ICU stay [P50(P25,P75), hour]

39(19.5,70)

43.5(19,75.5)

0.906

21(20,43)

42(22,68)

0.004

Post-hospital stay [P50(P25,P75), day]

10(6.5,11.5)

10(7,12)

0.799

8(7,11)

9(7,11)

0.773

Transfusion: platelet [P50(P25,P75), unit]

0(0,0)

0(0,1)

0.042

0(0,0)

0(0,1)

0.000

Transfusion: erythrocyte [P50(P25,P75), unit]

1.5(0,5.75)

2(0,4)

0.799

0(0,2)

0(0,4)

0.549

Transfusion: plasma [P50(P25,P75), unit]

5.5(3,11.5)

7(4,11.5)

0.261

3.5(0,5)

4.5(3,7)

0.037

Transfusion: cryoprecipitate [P50(P25,P75), unit]

0(0,8)

0(0,17.5)

0.354

0(0,0)

0(0,0)

0.028

Mortality [n(%)]

2(6.9)

3(11.5)

0.550

1(2.2)

3(6.4)

0.339

Post-operative EF [P50(P25,P75),%]

54(44.5,60.5)

51.5(42,62)

0.933

58.5(53,63)

54(45,61)

0.140

Post-operative SV[P50(P25,P75),ml]

67(50,91.5)

65(51.5,82)

0.418

64.5(54,84)

56(40,66)

0.007

Post-operative CO [P50(P25,P75), L/min]

6.8(4.4,7.7)

6(3.9,7.6)

0.522

5.9(4.8,7.0)

4.8(3.6,6.4)

0.002

Post-operative HR [P50(P25,P75),/min]

91(82,97)

87(78,100)

0.899

90.5(75,104)

86(77,98)

0.551

Post-operative FS [P50(P25,P75), %]

28(22.5,32)

27(21.5,32)

0.692

30(27,34)

28(21,33)

0.294

  1. DN del Nido, HTK histidine-tryptophan-ketoglutarate, Dop dopamine, NE norepinephrine, E epinephrine, MV mechanical ventilation, ICU intensive care unit, EF ejection fraction, SV stroke volume, CO cardiac output, HR heart rate, FS fraction shortening