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Table 3 Perioperative details of paired patients undergone complex valve surgery

From: Del Nido versus HTK cardioplegia for myocardial protection during adult complex valve surgery: a retrospective study

 

DN (n = 73)

HTK (n = 73)

P-value

Valves:aortic + mitral + tricuspid [n(%)]

19 (26.0)

16 (21.9)

0.561

Valves:aortic + mitral [n(%)]

25 (34.2)

31 (42.5)

0.307

Valves:aortic + tricuspid [n(%)]

5 (6.8)

6 (8.2)

0.754

Valves: mitral + tricuspid [n(%)]

22 (30.1)

18 (24.7)

0.458

Valves:pulmonary + tricuspid [n(%)]

2 (2.7)

2 (2.7)

1.000

Combined with aorta operation [n(%)]

16 (21.9)

20 (27.4)

0.442

Combined with CABG operation [n(%)]^

24 (32.9)

25 (34.2)

0.861

Combined with others# operation [n(%)]

30 (41.1)

26 (35.6)

0.496

Aortic valve mechanic [n(%)]

23 (31.5)

20 (27.4)

0.586

Cardiopulmonary bypass time [P50(P25,P75), min]

149 (116,181)

158 (126,187)

0.232

Cardioplegia: numbers of infusion [P50(P25,P75)]

2 (1,3)

1 (1,2)

0.000

Cardioplegia: infusion interval time [P50(P25,P75), min]

50 (43,63)

83 (60,95)

0.000

Cardioplegia: antegrade infusion [n(%)]

67 (91.8)

70 (95.9)

0.302

Cardioplegia: volume [P50(P25,P75), mL]

1265 (1000,1500)

1900 (1500,2000)

0.000

Aortic clamping time [P50(P25,P75), min]

107 (74,134)

100 (83,133)

0.795

Return to spontaneous rhythm [n(%)]

64 (87.7)

38 (52.1)

0.000

MV time [P50(P25,P75), hour]

15 (11,25)

19 (14,27)

0.131

ICU stay [P50(P25,P75), hour]

29 (20,68)

43 (21,75)

0.024

Post-hospital stay [P50(P25,P75), day]

8 (7,11)

9 (7,11)

0.933

Dop [P50(P25,P75)]

2 (1,3)

3 (1,4)

0.341

Ne [P50(P25,P75)]

3 (1,3)

3 (2,4)

0.153

E [P50(P25,P75)]

1 (0,2)

1 (0,3)

0.161

Transfusion: platelet [P50(P25,P75), unit]

0 (0,0)

0 (0,1)

0.000

Transfusion: erythrocyte [P50(P25,P75), unit]

0.75 (0,4)

0 (0,4)

0.682

Transfusion: plasma [P50(P25,P75), unit]

4 (0,7)

5 (3,9)

0.034

Transfusion: cryoprecipitate [P50(P25,P75), unit]

0 (0,0)

0 (0,16)

0.031

Mortality [n(%)]

3 (4.1)

6 (8.2)

0.302

Postoperative low cardiac output [n(%)]

6 (8.2)

12 (16.4)

0.131

Postoperative arrhythmia [n(%)]

9 (12.3)

19 (26.0)

0.036

Postoperative AKI [n(%)]

18 (24.7)

20 (27.4)

0.706

Postoperative ALI [n(%)]

3 (4.1)

2 (2.7)

0.649

Postoperative MODS [n(%)]

4 (7)

5 (7)

0.731

Postoperative lung injury [n(%)]

19 (26.0)

19 (26.0)

1.000

Postoperative CNS inury [n(%)]

3 (4.1)

2 (2.7)

0.649

Postoperative stress ulcer [n(%)]

1 (1.4)

3 (4.1)

0.311

  1. Others #: maze/congenital heart defect/cardiac tumor, or redo/mini procedures.(DN/HTK was 11/9 in maze, 5/2 in congenital heart defect, 1/5 in cardiac tumor, 6/4 in redo, 7/7 in mini/laparoscopic procedures, respectively)
  2. DN, del Nido; HTK, histidine-tryptophan-ketoglutarate; CABG, coronary artery bypass graft; MV, mechanical ventilation; ICU, intensive care unit; Dop, dopamine; NE, norepinephrine; E, epinephrine; AKI, acute kidney injury; ALI, acute liver injury; MODS, multiple organ dysfuntion syndrome; CNS, central nervous system