Prognosis in patients with coronary heart disease and breath-holding limitations: a free-breathing cardiac magnetic resonance protocol at 3.0 T

Table 3 Cox proportional hazards regression analysis for MACE

Univariate predictors	HR/X²	95.0% CI	P-value
IS (per 1% increase)	1.05	1.03–1.07	< 0.001
LVEF (per 1% increase)	0.94	0.92–0.96	< 0.001
LVEDM (per 1 g increase)	1.01	1.00–1.02	0.032
3D-GPLS (per 1% decrease)	1.15	1.09–1.29	< 0.001
Heart failure classification	36.2		< 0.001
Male gender	0.01		0.929
Age (per 1 year increase)	1.06	1.03–1.09	0.030
Diabetes mellitus	4.24		0.039
Hypertension	8.13		0.004
Hyperhomocysteinemia	0.08		0.783
Smoker	0.00		0.989
PCI	3.26		0.071
Aspirin use	3.14		0.076
ACE inhibitor use	4.43		0.035
Beta-blocker use	3.74		0.053
Calcium channel blocker use	1.41		0.235
Statin use	0.50		0.478

Multivariate predictors	HR	95.0% CI	P value
IS (per 1% increase)	1.02	1.00–1.05	0.048
LVEF (per 1% increase)	1.03	0.96–1.09	0.428
3D-GPLS (per 1% decrease)	1.15	0.92–1.44	0.199
HFpEF	0.20	0.04–0.98	0.048

IS infarction size, LVEF left ventricular ejection fraction, LVEDV left ventricular end-diastolic volume, LVESV left ventricular end-systolic volume, LVSV left ventricular systolic volume, LVEDM left ventricular end-systolic mass, 3D-GPLS three-dimensional global peak longituditial strain, PCI percutaneous coronary intervention, HF hear failure, HFpEF heart failure with preserved EF

ISSN: 1471-2261