Fig.1

Cardiac function was rescued by RSV. All rats (5 rats in each group) were survived and the effects of RSV on cardiac function were evaluated using echocardiography on the ninetieth day after immunization. Our results showed that myocardial dilation and cardiac hypertrophy were significantly ameliorated and cardiac function was enhanced by RSV in rats with DCM. a Heart weight, b body weight, c heart weight/body weight, d LVEDD, Left ventricular end diastolic diameter, e LVESD, left ventricular end systolic diameter; f LVPWT, Left ventricular posterior wall thickness; g LIVST, Left interventricular septal thickness; h LVEF, Left ventricular ejection fraction; i LVSF, Left ventricular shortening fraction. RSV, Resveratrol; DCM, dilated cardiomyopathy disease; RSV-L, low dose of RSV (10 mg/kg/d); RSV-H, high dose of RSV (50 mg/kg/d). Data were presented as mean ± SD. ***, P < 0.0001; **, P < 0.001; *, P < 0.05; ns, P > 0.05