Skip to main content

Table 1 Comparisons of the clinical characteristics between groups stratified by 28-days mortality

From: Comparing the impact on the prognosis of acute myocardial infarction critical patients of using midazolam, propofol, and dexmedetomidine for sedation

Variables N = 427 28-days p value
Mortality N = 102 Survival N = 325
MI     0.179
NSTEMI 121(28.3) 32(31.4) 89(27.4)  
AWSTEMI 126(29.5) 35(34.3) 91(28.0)  
NAWSTEMI 180(42.1) 35(34.3) 145(44.6)  
Age, years 66.9 ± 12.3 69.4 ± 13.3 66.2 ± 11.9 0.020
Male, n(%) 304(71.8) 69(67.6) 238(73.2) 0.274
BMI, kg/m2 28.0 ± 5.5 28.1 ± 5.9 27.9 ± 5.4 0.871
Past medical history     
Hypertension, n(%) 55(12.9) 23(22.5) 32(9.8) 0.001
Diabetes, n(%) 138(32.3) 38(37.2) 100(30.8) 0.222
CHF, n(%) 49(11.5) 17(16.7) 32(9.8) 0.059
COPD, n(%) 77(1.6) 17(16.7) 60(18.5) 0.681
Peripheral, n(%) 70(1.6) 19(18.6) 51(15.7) 0.485
Heart rate, bpm 86.7 ± 14.5 89.6 ± 17.8 85.7 ± 13.2 0.019
MBP, mmHg 77.2 ± 8.1 75.3 ± 9.8 77.8 ± 7.4 0.007
SpO2, % 97.5 ± 2.2 96.7 ± 3.3 97.8 ± 1.6 0.000
*RASS score 0(− 2,0)  − 0.5(− 3,0) 0(− 1,0) 0.128
Biochemistry     
WBC, K/uL 14.1 ± 7.1 16.8 ± 8.7 13.3 ± 6.4 0.000
PLT, K/uL 220.7 ± 99.0 223.4 ± 101.5 219.8 ± 98.3 0.753
HGB, g/dl 10.8 ± 2.0 10.7 ± 1.9 10.8 ± 2.1 0.788
TB, mg/dl 1.1 ± 2.5 1.7 ± 4.8 0.9 ± 0.7 0.008
Glu, mg/dl 181.8 ± 105.1 229.9 ± 122.7 166.6 ± 94.2 0.000
Scr, mg/dl 1.3 ± 1.2 1.7 ± 1.2 1.2 ± 1.2 0.000
Potassium, mEq/L 4.3 ± 0.7 4.3 ± 0.7 4.3 ± 0.7 0.995
&Serum tropoin, ng/ml 4.3 ± 0.5 7.6 ± 1.3 2.9 ± 0.3 0.000
Treatments     
Aspirin, n(%) 323(75.6) 55(53.9) 268(82.5) 0.000
Clopidogrel, n(%) 142(33.3) 28(27.4) 114(35.1) 0.154
Betablock, n(%) 257(83.6) 58(56.9) 299(92.0) 0.000
Stain, n(%) 287(67.2) 41(40.2) 246(75.7) 0.000
Vasopressor, n(%) 335(78.5) 94(92.2) 241(74.2) 0.000
Mechanical ventilation, n(%) 399(93.4) 96(94.1) 303(93.2) 0.752
#Revascularization, n(%) 299(70.0) 47(46.1) 252(77.5) 0.000
Propofol, n(%) 272(63.7) 45(44.1) 227(69.8) 0.000
Midazolam, n(%) 143(33.5) 56(54.9) 87(26.8) 0.000
Dexmedetomidine, n(%) 28(6.5) 2(2.0) 26(8.0) 0.032
Propofol + Midazolam 53(12.4) 17(16.6) 36(11.1) 0.135
Propofol + Dexmedetomidine 22(5.1) 1(1.0) 21(6.5) 0.036
Midazolam + Dexmedetomidine 13(3.0) 1(1.0) 12(3.7) 0.318
All three seditives 8(1.9) 0(0) 8(2.5) 0.207
  1. MI myocardial infarction; NSTEMI non-ST segment elevated myocardial infarction; AWSTEMI anterior wall ST segment elevated myocardial infarction; NAWSTEMI non-anterior wall ST segment elevated myocardial infarction; BMI body mass index; CHF congestive heart failure; COPD chronic obstructive pulmonary disease; MBP mean arterial pressure; WBC white blood cell; PLT platelet; HGB hemoglobin; TB total bilirubin; Glu glucose; Scr creatinine; *, 141 patients with RASS scores records, include 40 patients in mortality group and 101 in survival group; & 289 patients with serum tropoin record, include 201 patients in mortality group and 88 in survival group; #, include percutaneous coronary intervention and coronary artery bridge graft