Table 2 Comparison of demographic and baseline clinical characteristics of participants between low and high serum irisin groups
| Â | Low irisin group | High irisin group | p value |
|---|---|---|---|
N | 96 | 95 | Â |
Sex (F/M) | 66/30 | 75/20 | 0.109 |
Age (y) | 57.2 ± 8.4 | 56.2 ± 8.4 | 0.394 |
Smoking (%) | 31 (32.3%) | 7 (7.4%) | ≤ 0.001** |
Active physical activity (%) | 33 (34.4%) | 42 (44.2%) | 0.162 |
BMI (kg/m2) | 27.6 ± 2.3 | 27.4 ± 2.5 | 0.672 |
WC (cm) | 92.0 ± 7.4 | 91.2 ± 7.4 | 0.496 |
FPG (mmol/l) | 5.8 (5.5, 6.1) | 5.6 (5.4, 6.0) | 0.025* |
2hPG (mmol/l) | 7.9 (6.7, 9.6) | 7.6 (6.5, 9.0) | 0.460 |
TC (mmol/l) | 4.7 ± 1.1 | 4.6 ± 1.2 | 0.578 |
TG (mmol/l) | 1.6 (1.1, 2.3) | 1.5 (1.1, 2.2) | 0.535 |
LDL-C (mmol/l) | 2.7 ± 0.8 | 2.8 ± 0.7 | 0.395 |
HDL-C (mmol/l) | 1.1 ± 0.3 | 1.3 ± 0.3 | 0.005** |
SBP (mmHg) | 121.8 ± 15.4 | 123.6 ± 19.4 | 0.489 |
DBP (mmHg) | 78.7 ± 9.7 | 80.0 ± 10.6 | 0.385 |
Fasting insulin (mIU/l) | 10.2 ± 3.4 | 10.3 ± 4.5 | 0.790 |
HOMA-IR | 2.7 ± 1.0 | 2.7 ± 1.4 | 0.938 |
Serum creatinine (mmol/l) | 69.1 ± 16.1 | 68.2 ± 13.6 | 0.652 |
Serum irisin (ng/ml) | 10.96 (9.28, 12.29) | 16.60 (14.33, 19.86) | ≤ 0.001** |