Table 3 Baseline characteristics of patients with AS and CAD as well as of patients with and without periprocedural PCI separately
|  | Patients with CAD (n = 333) | TAVR + PCI (n = 120) | Isolated TAVR (n = 213) | P value |
|---|---|---|---|---|
Age (years) | 81.4 ± 6.1 | 81.3 ± 6.0 | 81.4 ± 6.1 | 0.88 |
Male (%) | 160 (48.0) | 66 (55.0) | 94 (44.1) | 0.06 |
Body mass index (BMI; kg/m2) | 26.6 ± 4.9 | 26.5 ± 4.7 | 26.7 ± 5.0 | 0.61 |
NYHA functional class | 3.0 ± 0.8 | 3.0 ± 0.7 | 3.0 ± 0.8 | 0.33 |
CCS class | 1.1 ± 1.4 | 0.9 ± 1.3 | 1.2 ± 1.5 | 0.14 |
Diabetes mellitus (%) | 98 (29.4) | 36 (30.0) | 62 (29.1) | 0.86 |
Prior myocardial infarction (%) | 73 (21.9) | 27 (22.5) | 46 (21.6) | 0.85 |
Previous TIA/stroke (%) | 42 (12.6) | 16. (13.3) | 26 (12.2) | 0.77 |
Carotid stenosis > 70% (%) | 17 (5.1) | 8 (6.7) | 9 (4.2) | 0.34 |
Atrial fibrillation (%) | 138 (41.4) | 49 (40.8) | 89 (41.8) | 0.87 |
COPD (%) | 180 (54.1) | 51 (42.9) | 129 (60.6) |  < 0.01 |
Severe PAH (%) | 67 (20.1) | 23 (19.2) | 44 (20.8) | 0.73 |
mPAP (mmHg) | 30.0 ± 11.4 | 28.7 ± 12.7 | 30.8 ± 10.5 | 0.08 |
LVEF (%) | 61.7 ± 22.1 | 63.5 ± 23.8 | 60.6 ± 21.0 | 0.26 |
Cardiac output (l/min) | 4.8 ± 8.3 | 4.3 ± 1.3 | 4.0 ± 1.2 | 0.15 |
Severe heart failure (%) | 21 (6.3) | 10 (8.4) | 11 (5.1) | 0.25 |
PCWP (mmHg) | 22.0 ± 9.9 | 20.5 ± 8.7 | 23.0 ± 10.6 | 0.22 |
Troponin T (ng/l) | 93.3 ± 646 | 51.7 ± 104 | 115.7 ± 798 | 0.23 |
Renal insufficiency (%) | 140 (42.0) | 52 (43.3) | 88 (41.3) | 0.72 |
Creatinine level (mg/dl) | 1.2 ± 0.7 | 1.2 ± 0.7 | 1.2 ± 0.8 | 0.94 |
Creatinine clearance (ml/min) | 51.8 ± 19.7 | 53.1 ± 21.6 | 51.1 ± 18.6 | 0.69 |
Aortic valve area (cm2) | 0.6 ± 0.22 | 0.7 ± 0.2 | 0.6 ± 0.2 | 0.02 |
MTPG (mmHg) | 35.1 ± 14.7 | 32.7 ± 12.4 | 36.3 ± 15.6 | 0.15 |
EuroSCORE II (%) | 6.2 ± 5.3 | 5.5 ± 4.0 | 6.6 ± 5.9 | 0.22 |
STS score | 6.9 ± 4.7 | 6.1 ± 3.9 | 7.3 ± 5.0 | 0.13 |
SYNTAX score baseline | 10.8 ± 8.8 | 14.9 ± 9.1 | 8.5 ± 7.9 |  < 0.001 |