Table 1 Baseline characteristics of the entire study population as well as of patients with and without CAD separately
|  | Overall population (n = 553) | CAD (n = 333) | No CAD (n = 220) | P value |
|---|---|---|---|---|
Age (years) | 81.1 ± 6.2 | 81.4 ± 6.1 | 80.6 ± 6.4 | 0.41 |
Male (%) | 242 (43.8) | 160 (48.0) | 82 (37.3) | 0.01 |
Body mass index (BMI; kg/m2) | 26.6 ± 4.7 | 26.6 ± 4.9 | 26.5 ± 4.5 | 0.73 |
NYHA functional class | 3.0 ± 0.7 | 3.0 ± 0.8 | 3.1 ± 0.7 | 0.47 |
CCS class | 1.1 ± 1.4 | 1.1 ± 1.4 | 1.0 ± 1.4 | 0.71 |
Diabetes mellitus (%) | 160 (28.9) | 98 (29.4) | 62 (28.2) | 0.75 |
Prior myocardial infarction (%) | 73 (13.2) | 73 (21.9) | 0 (0.0) |  < 0.001 |
Previous TIA/stroke (%) | 69 (12.5) | 42 (12.6) | 27 (12.3) | 0.91 |
Carotid stenosis > 70% (%) | 24 (4.3) | 17 (5.1) | 7 (3.2) | 0.27 |
Atrial fibrillation (%) | 236 (42.7) | 138 (41.4) | 98 (44.6) | 0.47 |
COPD (%) | 301 (54.4) | 180 (54.1) | 121 (55.5) | 0.77 |
Severe PAH (mmHg) | 118 (21.3) | 67 (20.1) | 51 (23.5) | 0.36 |
mPAP (mmHg) | 30.4 ± 11.9 | 30.0 ± 11.4 | 31.1 ± 12.7 | 0.57 |
LVEF (%) | 61.6 ± 21.5 | 61.7 ± 22.1 | 61.6 ± 20.7 | 0.61 |
Cardiac output (l/min) | 4.5 ± 6.6 | 4.8 ± 8.3 | 4.1 ± 1.1 | 0.80 |
Severe heart failure (%) | 35 (6.3) | 21 (6.3) | 14 (6.4) | 0.97 |
PCWP (mmHg) | 21.7 ± 10.3 | 22.0 ± 9.9 | 21.4 ± 10.9 | 0.64 |
Troponin T (ng/l) | 72.7 ± 495 | 93.3 ± 646 | 43.9 ± 68 | 0.30 |
Renal insufficiency (%) | 22 (40.1) | 140 (42.0) | 82 (37.3) | 0.26 |
Creatinine level (mg/dl) | 1.2 ± 0.7 | 1.2 ± 0.7 | 1.2 ± 0.7 | 0.24 |
Creatinine clearance (ml/min) | 51.9 ± 19.7 | 51.8 ± 19.7 | 51.9 ± 19.7 | 0.95 |
Aortic valve area (cm2) | 0.6 ± 0.2 | 0.6 ± 0.22 | 0.6 ± 0.2 | 0.71 |
MTPG (mmHg) | 36.4 ± 15.7 | 35.1 ± 14.7 | 38.5 ± 17.2 | 0.11 |
EuroSCORE II (%) | 5.8 ± 4.9 | 6.2 ± 5.3 | 5.2 ± 4.1 | 0.02 |
STS score | 6.9 ± 5.0 | 6.9 ± 4.7 | 6.8 ± 5.3 | 0.51 |
SYNTAX score baseline | 6.5 ± 8.7 | 10.8 ± 8.8 | 0.0 |  < 0.001 |