Hyperoxia during extracorporeal cardiopulmonary resuscitation for refractory cardiac arrest is associated with severe circulatory failure and increased mortality

Table 3 Variables associated with in-hospital mortality (multivariable analysis)

Variable	Odds ratio	95% CI	p value
(a) Model using co-variables significantly associated with mortality in univariate analysis
Low flow duration	1.03	0.96–1.11	0.39
First Lactate	1.19	0.92–1.53	0.18
Mean BP	0.86	0.69–1.07	0.17
Mean PaO₂	1.02	1.01–1.05	0.02
(b) Model using co-variables frequently associated with mortality in univariate analysis
Age	1.04	0.92–1.17	0.55
No Flow duration	0.01	0.01–1.38	0.09
Low flow duration	1.26	0.99–1.59	0.06
ECMO duration	1.01	0.99–1.03	0.25
Shockable rhythm	0.01	0.01–3.29	0.12
Localization (IH vs OH)	0.05	0.01–7.32	0.24
Mean PaO₂	1.07	1.01–1.13	0.03
(c) Models with 2 co-variables
Mean PaO₂	1.04	1.02–1.08	0.009
No flow	0.62	0.31–1.07	0.121
Mean PaO₂	1.02	1.01–1.06	0.011
Low flow	1.03	0.98–1.11	0.232
Mean PaO₂	1.03	1.01–1.06	0.013
Shockable rhythm	0.42	0.06–2.86	0.383

CI confidence interval. Odds ratio for continuous variables are calculated per unit change for each variable (1 mmol/L for lactate, 1 mmHg for mean BP, 1 y for age, 1 min for no flow and low flow duration, 1 h for ECMO duration, 1 mmHg for mean PaO₂)

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