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Table 1 Characteristics of patients

From: Hyperoxia during extracorporeal cardiopulmonary resuscitation for refractory cardiac arrest is associated with severe circulatory failure and increased mortality

 

All pts

(n = 44)

Non survivors

(n = 33)

Survivors

(n = 11)

p value

Age (years), mean (SD)

52 (14)

54 (12)

48 (19)

0.456

Male sex, n (%)

31 (70)

24 (73)

7 (63)

0.567

SAPS 2, mean (SD)

83 (13)

85 (14)

76 (6)

0.003

ICU LOS (days), median (IQR)

2.6 (18.8)

1.5 (4.3)

22.9 (28.8)

< 0.001

HOSP LOS, (days), median (IQR)

2.8 (27.3)

1.6 (4.2)

51.4 (38.0)

< 0.001

ECMO Weaning, n (%)

15 (34)

4 (12)

11 (100)

< 0.001

Survival (Hospital), n (%)

11 (25)

0 (0)

11 (100)

 

ECMO duration (hours), median (IQR)

43 (106)

28 (106)

81 (74)

0.024

Location of CA

   

0.858

OHCA, n (%)

27 (61)

20 (65)

7 (63)

 

IHCA, n (%)

17 (39)

13 (35)

4 (37)

 

Initial rhythm

   

0.141

VF, n (%)

23 (52)

16 (49)

7 (64)

 

PEA, n (%)

14 (32)

11 (33)

3 (27)

 

Asystole, n (%)

6 (14)

6 (18)

0 (0)

 

Unknown, n (%)

1 (2)

0 (0)

1 (9)

 

Shockable Rhythm

23 (52)

16 (48)

7 (64)

0.214

No flow (minutes), mean (SD)

1.2 (2.0)

1.1 (2.0)

1.5 (2.2)

0.572

Low flow (minutes), mean (SD)

68 (23)

73 (22)

51 (18)

0.005

Mean PaO2 (first 24 h, mmHg), mean (SD)

269 (124)

306 (121)

164 (53)

0.001

Mean PaCO2 (first 24 h, mmHg), mean (SD)

37 (6)

36 (7)

38 (3)

0.525

First lactate (mmol/L), mean (SD)

13.4 (5.9)

14.9 (5.8)

9.4 (4.1)

0.004

Mean BP (first 24 h), mean (SD)

67 (12)

64 (12)

75 (5)

0.007

Pulse Pressure (first 24 h), mean (SD)

20 (13)

18 (12)

25 (13)

0.149

Coronarography, n (%)

22 (50)

16 (48)

6 (54)

0.728

PTCA, n (%)

17 (39)

11 (33)

6 (54)

0.211

NA (μg/kg/min, first 72 h), median (IQR)

0.25 (0.44)

0.37 (0.54)

0.12 (0.13)

0.006

ADRE, (μg/kg/min, first 72 h), median (IQR)

0.02 (0.13)

0.06 (0.20)

0.00 (0.04)

0.043

Total catecholamines (NA + ADRE, first 72 h)

0.36 (0.73)

0.54 (0.67)

0.12 (0.16)

0.002

Cristalloid (ml/kg/h, first 72 h), mean (SD)

6.0 (9.8)

7.3 (11.2)

2.4 (0.8)

0.023

Packed RBC (n, first 72 h), mean (SD)

5.2 (4.7)

5.5 (4.8)

4.4 (4.4)

0.449

FFP (n, first 72 h), mean (SD)

2.4 (3.0)

2.6 (3.1)

1.6 (2.7)

0.294

  1. ADRE adrenaline, BP blood pressure, ECMO extra-corporeal membrane oxygenation, FFP fresh frozen plasma, ICU intensive care unit, IHCA in-hospital cardiac arrest, LOS length of stay, NA noradrenaline, OHCA out-of-hospital cardiac arrest, PEA pulseless electrical activity, PTCA percutaneous transluminal coronary angioplasty, RBC red blood cells, SAPS simplified acute physiology score, VF ventricular fibrillation
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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