Table 3 Subgroup analyses for association between CHD and educational attainment
Subgroup | Number of studies (n CHD cases, n non-CHD) | OR (95% CI) for not achieving educational outcome per subgroup | Test for subgroup differences p value |
|---|---|---|---|
Not obtaining a university degree | |||
Geographic area | |||
 Europe | 8 (9871 vs. 93,221) | 1.24 [1.03; 1.49] | 0.03 |
 North America | 1 (124 vs. 124) | 1.49 [0.88; 2.52] |  |
 Middle East | 2 (492 vs. 753) | 2.29 [1.50; 3.51] |  |
Year of the study | |||
 Before 2015 | 7 (3064 vs. 23,807) | 1.47 [1.08; 2.02] | 0.55 |
 2015 and after | 4 (7423 vs. 70,291) | 1.30 [1.01; 1.67] |  |
Proportion of females | |||
  ≥ 50% | 4 (7630 vs. 70,402) | 1.75 [1.30; 2.35 | 0.14 |
  < 50% | 6 (2087 vs. 15,142) | 1.17 [0.75; 1.84] |  |
Proportion of severe disease | |||
  ≥ 10% | 6 (2376 vs. 8053) | 1.49 [1.10; 2.02] | 0.43 |
  < 10% | 5 (8111 vs. 86,045) | 1.25 [0.93; 1.69] |  |
Not completing secondary education | |||
 Geographic area | |||
 Europe | 8 (11,349 vs. 155,173) | 1.24 [1.01; 1.53] |  |
 North America | 1 (124 vs. 124) | 1.00 [0.14; 7.21] | 0.03 |
 Middle East | 1 (347 vs. 353) | 2.14 [1.50; 3.04] |  |
Year of the study | |||
 Before 2015 | 5 (4150 vs. 35,173) | 1.21 [0.87; 1.67] | 0.34 |
 2015 and after | 5 (7670 vs. 120,477) | 1.52 [1.08; 2.14] |  |
Proportion of females | |||
  ≥ 50% | 4 (7630 vs. 70,402) | 1.88 [1.22; 2.89] | 0.04 |
  < 50% | 5 (2118 vs. 64,717) | 1.01 [0.74; 1.40] |  |
Proportion of severe disease | |||
  ≥ 10% | 6 (2478 vs. 57,839) | 1.39 [0.99; 1.94] | 0.77 |
  < 10% | 4 (9342 vs. 97,811) | 1.30 [1.02; 1.67] |  |
Not completing vocational training | |||
Geographic area | |||
 Europe | 6 (9693 vs. 140,872) | 1.12 [1.00; 1.25] |  |
 North America | 1 (124 vs. 124) | 0.47 [0.17; 1.31] | 0.10 |
 Middle East | – | – |  |
Year of the study | |||
 Before 2015 | 3 (2267 vs. 20,866) | 1.03 [0.74; 1.43] | 0.43 |
 2015 and after | 4 (7550 vs. 120,130) | 1.20 [0.96; 1.51] |  |
Proportion of females | |||
  ≥ 50% | 3 (7283 vs. 70,049) | 1.10 [0.73; 1.65] | 0.52 |
  < 50% | 3 (462 vs. 50,416) | 1.28 [1.02; 1.61] |  |
Proportion of severe disease | |||
  ≥ 10% | 3 (515 vs. 50,329) | 1.04 [0.65; 1.67] | 0.87 |
  < 10% | 4 (9302 vs. 90,667) | 1.08 [0.97; 1.20] |  |