Table 2 Baseline clinical characteristics of the study population
Clinical characteristics | All study patients (n = 83) | Non-PH (n = 65) | PH (n = 18) | P |
|---|---|---|---|---|
Birth history | ||||
Male | 46(55%) | 35(54%) | 11(61%) | 0.583 |
Birth weight, g | 1078.1 ± 194.0 | 1108.5 ± 185.8 | 968.1 ± 187.7 | 0.006 |
Gestational age, weeks | 28.3 ± 1.3 | 28.4 ± 1.2 | 27.9 ± 1.3 | 0.132 |
5-min Apgar scores | ||||
0–3 | 1(1%) | 0(0) | 1(6%) | |
4–7 | 15(18%) | 13(20%) | 2(11%) | 0.120 |
8–10 | 67(81%) | 52(80%) | 15(83%) | |
Small for gestational age | 5(6%) | 2(3%) | 3(17%) | 0.066 |
Maternal medical history | ||||
Cesarean section | 41(49%) | 32(49%) | 9(50%) | 0.954 |
Maternal age, ≥ 35 | 14(17%) | 9(14%) | 5(28%) | 0.162 |
Gestational diabetes | 7(8%) | 5(8%) | 2(11%) | 0.644 |
Gestational hypertension | 14(17%) | 11(17%) | 3(17%) | 0.979 |
PPROM | 18(22%) | 14(22%) | 4(22%) | 0.950 |
Placental abruption | 11(13%) | 9(14%) | 2(11%) | 0.762 |
Clinical characteristics | ||||
BPD severity | ||||
mild | 38(46%) | 32(49%) | 6(33%) | |
moderate | 27(32%) | 22(34%) | 5(28%) | 0.130 |
severe | 18(22%) | 11(17%) | 7(39%) | |
Pulmonary surfactant | 73(88%) | 56(86%) | 17(94%) | 0.339 |
Respiratory distress syndrome | 82(99%) | 64(98%) | 18(100%) | 0.597 |
Duration of O2 therapy, days | 58.9 ± 28.0 | 55.5 ± 27.8 | 70.9 ± 26.1 | 0.038 |
Duration of mechanical ventilation, days | 51.4 ± 27.5 | 48.0 ± 27.2 | 63.9 ± 25.4 | 0.028 |
Duration of hospitalization, days | 75.0 ± 24.5 | 73.1 ± 25.2 | 81.9 ± 20.8 | 0.178 |
Hypoxemia | 81(98%) | 63(97%) | 18(100%) | 0.451 |
NEC, stage ≥ 2 | 6(7%) | 5(8%) | 1(6%) | 1.000 |
Home oxygen | 3(4%) | 2(3%) | 1(6%) | 0.525 |
Death | 3(4%) | 1(2%) | 2(11%) | 0.117 |
Transthoracic echocardiography | ||||
Patent ductus arteriosus | 36(43%) | 21(32%) | 15(83%) | 0.001 |
Atrial septal defect | 66(80%) | 51(78%) | 15(83%) | 0.650 |
Patent foramen ovale | 34(41%) | 29(45%) | 5(28%) | 0.199 |
Ventricular septal defect | 1(1%) | 1(2%) | 0(0) | 0.597 |