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Table 1 Baseline characteristics of patients with ischemic cardiomyopathy with and without events

From: Human epididymis protein 4: a novel predictor of ischemic cardiomyopathy

Variables

Events group

(n = 45)

No events group

(n = 51)

Total

(n = 96)

P-value

Age (y)

75 (70–81)

68 (61–73)

71 (65–77)

< 0.001

Male, n (%)

28 (62.2%)

35 (68.6%)

63 (65.6%)

0.510

BMI (kg/m2)

23.35 ± 3.48

24.09 ± 3.07

23.78 ± 3.24

0.326

Hypertension, n (%)

28 (62.2%)

30 (58.8%)

58 (60.4%)

0.734

Atrial fibrillation, n (%)

8 (17.8%)

4 (7.8%)

12 (12.5%)

0.142

Diabetes, n (%)

15 (33.3%)

19 (37.3%)

34 (35.4%)

0.688

NYHA-FC

   

0.006

II, n (%)

7 (15.6%)

21 (41.2%)

28 (29.2%)

 

III/IV, n (%)

38 (84.4%)

30 (58.8%)

68 (70.9%)

 

LVEF (%)

32 (27–42)

33 (30–42)

33 (29–42)

0.368

LVEDD/BSA (mm/m2)

35.7(33.8–39.9)

35.6(33.6–38.5)

35.6(33.6–39.2)

0.51

NT- proBNP (ng/L)

7084.0 (3147.0–15,175.5)

1874.5 (937.7–4902.7)

3682.0 (1247.0–21,403.4)

 < 0.001

HE4 (pmol/L)

188.7 (113.3–326.8)

92.9 (61.50–123.2)

117.6 (80.1–196.8)

 < 0.001

eGFR (mL/min/1.73 m2)

53.72 ± 23.48

77.04 ± 25.48

66.11 ± 27.09

 < 0.001

WBC (109/L)

6.74 (5.35–8.85)

6.26 (5.33–7.15)

6.48 (5.34–7.84)

0.187

LDL-C(mmol/L)

2.44 (1.88–2.79)

2.33 (1.73–3.36)

2.37 (1.85–3.07)

0.519

ALT (U/L)

16.5 (11.0–42.8)

18.5 (13.8–31.7)

17.6 (12.2–35.4)

0.436

HbA1c (%)

5.75 (5.50–6.50)

6.00 (5.53–6.93)

5.90 (5.50–6.70)

0.389

CK-MB(U/L)

13.0 (0.5–22.0)

14.5 (10.0–20.0)

13.0 (0–20.0)

0.887

PCI, n (%)

20 (44.4%)

30 (58.8%)

50 (52.1%)

0.159

Diuretics, n (%)

32 (71.1%)

30 (58.8%)

62 (64.6%)

0.209

ACEI/ARB/ARNI, n (%)

34 (81.0%)

46 (90.2%)

80 (86.0%)

0.201

β-Blocker, n (%)

37 (82.2%)

47 (92.2%)

84 (87.5%)

0.142

  1. ACEI angiotensin-converting enzyme inhibitor, ALT alanine aminotransferase, ARB angiotensin receptor blocker, ARNI angiotensin receptor and enkephalinase inhibitor, BMI body mass index, CK-MB creatine kinase isoenzyme-MB, eGFR estimated glomerular filtration rate, HbA1c hemoglobin A1c, HE4 human epididymis protein, LDL low-density lipoprotein, LVEDD/BSA left ventricular end diastolic dimension/body surface area, LVEF left ventricular ejection fraction, MDRD Modification of Diet in Renal Disease, NT-proBNP N-terminal prohormone of B-type natriuretic peptide, NYHA-FC New York Heart Association Functional Classification, PCI percutaneous coronary intervention, WBC white blood cells