Table 4 Spirometric outcomes and exercise outcomes of patients and healthy controls
Item | 1 years after VSD closure | 5 years after VSD closure | ||||
|---|---|---|---|---|---|---|
Patients | Controls | p | Patients | Controls | p | |
FVC(%) | 112.62 ± 9.43 | 113.27 ± 10.04 | 0.789 | 114.46 ± 10.10 | 114.64 ± 10.12 | 0.965 |
FEV1(%) | 92.77 ± 8.92 | 93.71 ± 9.14 | 0.640 | 94.13 ± 9.09 | 93.19 ± 10.40 | 0.532 |
PEF(%) | 105.65 ± 9.35 | 106.88 ± 10.39 | 0.334 | 104.80 ± 8.56 | 104.51 ± 9.19 | 0.782 |
FEV1/FVC | 82.32 ± 2.58 | 82.88 ± 6.08 | 0.531 | 82.23 ± 3.21 | 81.44 ± 7.49 | 0.154 |
Maximal workload(W) | 218.17 ± 33.60 | 284.94 ± 45.28 | < 0.001 | 223.44 ± 33.73 | 280.44 ± 45.60 | < 0.001 |
Maximal workload(W/kg) | 3.28 ± 0.10 | 4.49 ± 0.16 | < 0.001 | 3.36 ± 0.10 | 4.42 ± 0.21 | < 0.001 |
Peak heart rate (beats/min) | 179 ± 6.50 | 182 ± 8.69 | 0.083 | 180 ± 8.61 | 181 ± 10.03 | 0.289 |
Minute ventilation (L/kg/minute) | 1.50 ± 0.27 | 1.89 ± 0.36 | < 0.001 | 1.55 ± 0.31 | 2.02 ± 0.33 | < 0.001 |
Peak oxygen uptake (ml/min) | 2496 ± 284 | 3218 ± 440 | < 0.001 | 2531 ± 288 | 3299 ± 370 | < 0.001 |
Peak oxygen uptake(ml/kg/min) | 37.76 ± 2.35 | 50.89 ± 2.48 | < 0.001 | 38.30 ± 2.63 | 52.36 ± 3.45 | < 0.001 |
Peak carbon dioxide excretion(ml/kg/min) | 50.62 ± 4.16 | 69.41 ± 5.29 | < 0.001 | 51.42 ± 5.06 | 71.90 ± 6.66 | < 0.001 |
Peak respiratory-exchange-ratio | 1.34 ± 0.06 | 1.36 ± 0.07 | 0.058 | 1.34 ± 0.008 | 1.37 ± 0.08 | 0.078 |
Absolute anaerobic threshold | ||||||
Oxygen uptake(ml/kg/min) | 22.55 ± 4.33 | 30.64 ± 6.13 | < 0.001 | 22.21 ± 4.53 | 32.04 ± 5.67 | < 0.001 |
Maximal workload(W/kg) | 1.99 ± 0.20 | 2.71 ± 0.56 | < 0.001 | 1.91 ± 0.44 | 2.67 ± 0.67 | < 0.001 |
Heart rate(beats/min) | 140 ± 10.98 | 158 ± 11.34 | < 0.001 | 143 ± 11.93 | 160 ± 13.38 | < 0.001 |