Patients | Events | Two-year cumulative incidence proportion (95% CI) | Unadjusted IRR (95% CI) | Adjusted IRR* (95% CI) | |
---|---|---|---|---|---|
MACE | |||||
2004–2006 | 4847 | 302 | 6.3% (5.6–7.0) | Reference | Reference |
2007–2009 | 6104 | 312 | 5.2% (4.6–5.7) | 0.81 (0.69–0.96) | 0.81 (0.69–0.95) |
2010–2012 | 5547 | 243 | 4.2% (3.9–5.0) | 0.69 (0.59–0.82) | 0.65 (0.55–0.78) |
2013–2016 | 7042 | 272 | 3.9% (3.5–4.4) | 0.61 (0.52–0.72) | 0.57 (0.48–0.68) |
Myocardial infarction | |||||
2004–2006 | 4847 | 154 | 3.2% (2.8–3.8) | Reference | Reference |
2007–2009 | 6104 | 173 | 2.9% (2.5–3.3) | 0.89 (0.71–1.10) | 0.89 (0.72–1.11) |
2010–2012 | 5547 | 125 | 2.3% (1.0–2.7) | 0.70 (0.55–0.89) | 0.68 (0.54–0.87) |
2013–2016 | 7042 | 175 | 2.5% (2.2–2.9) | 0.77 (0.62–0.96) | 0.75 (0.60–0.93) |
Ischemic stroke | |||||
2004–2006 | 4847 | 72 | 1.5% (1.2–1.9) | Reference | Reference |
2007–2009 | 6104 | 69 | 1.2% (0.9–1.5) | 0.76 (0.54–1.05) | 0.71 (0.51–0.99) |
2010–2012 | 5547 | 64 | 1.2% (0.9–1.5) | 0.77 (0.55–1.07) | 0.65 (0.46–0.92) |
2013–2016 | 7042 | 62 | 0.9% (0.7–1.1) | 0.58 (0.42–0.82) | 0.48 (0.34–0.68) |
Cardiac death | |||||
2004–2006 | 4847 | 102 | 2.1% (1.8–2.6) | Reference | Reference |
2007–2009 | 6104 | 99 | 1.6% (1.4–2.0) | 0.77 (0.58–1.01) | 0.77 (0.58–1.87) |
2010–2012 | 5547 | 65 | 1.2% (0.9–1.5) | 0.55 (0.40–0.76) | 0.52 (0.38–0.71) |
2013–2016 | 7042 | 50 | 0.7% (0.5–0.9) | 0.33 (0.24–0.47) | 0.31 (0.22–0.44) |
Death | |||||
2004–2006 | 4847 | 229 | 4.7% (4.2–5.4) | Reference | Reference |
2007–2009 | 6104 | 270 | 4.4% (3.9–5.0) | 0.93 (0.78–1.11) | 0.95 (0.79–1.13) |
2010–2012 | 5547 | 219 | 4.0% (3.5–4.5) | 0.83 (0.69–1.00) | 0.80 (0.66–0.97) |
2013–2016 | 7042 | 216 | 3.1% (2.7–3.5) | 0.64 (0.53–0.77) | 0.61 (0.51–0.74) |