Patients | Events | Two-year cumultive incidence proportion (95% CI) | Unadjusted IRR (95% CI) | Adjusted IRR* (95% CI) | |
---|---|---|---|---|---|
MACE | |||||
2004–2006 | 1066 | 89 | 8.4% (6.9–10.3) | Reference | Reference |
2007–2009 | 1507 | 126 | 8.5% (7.2–10.0) | 1.01 (0.77–1.33) | 0.96 (0.73–1.27) |
2010–2012 | 1523 | 94 | 6.2% (5.2–7.6) | 0.73 (0.55–1.98) | 0.67 (0.50–0.91) |
2013–2016 | 1835 | 121 | 6.7% (5.6–7.9) | 0.78 (0.59–1.03) | 0.70 (0.53–0.93) |
Myocardial infarction | |||||
2004–2006 | 1066 | 42 | 4.0% (3.0–5.4) | Reference | Reference |
2007–2009 | 1507 | 57 | 3.9% (3.0–5.0) | 0.97 (0.65–1.45) | 0.96 (0.64–1.43) |
2010–2012 | 1523 | 61 | 4.1% (3.2–5.2) | 1.02 (0.69–1.51) | 0.97 (0.65–1.44) |
2013–2016 | 1835 | 66 | 3.7% (2.9–4.7) | 0.91 (0.61–1.34) | 0.85 (0.57–1.25) |
Ischemic stroke | |||||
2004–2006 | 1066 | 36 | 3.4% (2.5–4.7) | Reference | Reference |
2007–2009 | 1507 | 40 | 2.7% (2.0–3.7) | 0.79 (0.50–1.24) | 0.76 (0.48–1.21) |
2010–2012 | 1523 | 24 | 1.6% (1.1–2.4) | 0.46 (0.27–0.78) | 0.40 (0.24–0.69) |
2013–2016 | 1835 | 35 | 2.0% (1.4–2.7) | 0.56 (0.35–0.89) | 0.47 (0.29–0.76) |
Cardiac death | |||||
2004–2006 | 1066 | 24 | 2.3% (1.5–3.4) | Reference | Reference |
2007–2009 | 1507 | 41 | 2.8% (2.1–3.8) | 1.22 (0.74–2.20) | 1.12 (0.67–1.87) |
2010–2012 | 1523 | 17 | 1.1% (0.7–1.8) | 0.50 (0.27–0.92) | 0.45 (0.24–0.85) |
2013–2016 | 1835 | 30 | 1.7% (1.2–2.4) | 0.73 (0.42–1.24) | 0.65 (0.38–1.14) |
Death | |||||
2004–2006 | 1066 | 64 | 6.0% (4.7–7.6) | Reference | Reference |
2007–2009 | 1507 | 115 | 7.6% (6.4–9.1) | 1.28 (0.95–1.74) | 1.21 (0.89–1.64) |
2010–2012 | 1523 | 85 | 5.6% (4.5–6.9) | 0.93 (0.67–1.28) | 0.84 (0.61–1.17) |
2013–2016 | 1835 | 97 | 5.3% (4.4–6.4) | 0.88 (0.64–1.21) | 0.78 (0.56–1.06) |