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Table 1 Baseline data of aortic aneurysm patients in intensive care unit after open surgery

From: Association between anion gap and mortality of aortic aneurysm in intensive care unit after open surgery

Variables

 

ICU-Survival

(N = 377)

ICU-Death

(N = 28)

P value

General condition

 

Admission type

  

 < 0.001

 

ELECTIVE

282 (74.8%)

8 (28.6%)

 
 

EMERGENCY

86 (22.8%)

20 (71.4%)

 
 

URGENT

9 (2.4%)

0 (0.0%)

 
 

Death in hospital

2 (0.5%)

28 (100.0%)

 < 0.001

 

Death within 90 days

8 (2.1%)

28 (100.0%)

 < 0.001

 

Death within 365 days

20 (5.3%)

28 (100.0%)

 < 0.001

 

LOS in hospital (days)

9.06 [6.27, 14.15]

12.00 [4.07, 19.01]

 < 0.001

 

LOS in intensive care unit (days)

3.08 [1.86, 6.81]

11.88 [2.65, 19.19]

0.782

 

Age (years)

68.58 [59.14, 75.40]

76.80 [70.14, 80.96]

 < 0.001

 

Type of aortic aneurysm

  

 < 0.001

 

Abdominal aneurysm without mention of rupture

101 (26.8%)

8 (28.6%)

 
 

Abdominal aneurysm, ruptured

25 (6.6%)

10 (35.7%)

 
 

Thoracic aneurysm without mention of rupture

216 (57.3%)

5 (17.9%)

 
 

Thoracic aneurysm, ruptured

5 (1.3%)

1 (3.6%)

 
 

Thoracoabdominal aneurysm, ruptured

5 (1.3%)

2 (7.1%)

 
 

Thoracoabdominal aneurysm, without mention of rupture

25 (6.6%)

2 (7.1%)

 
 

Male

248 (65.8%)

13 (46.4%)

0.063

 

Aortic rupture

35 (9.3%)

13 (46.4%)

 < 0.001

Comorbidity

 

Sepsis

6 (1.6%)

6 (21.4%)

 < 0.001

 

Chronic pulmonary diseases

81 (21.5%)

7 (25.0%)

0.843

 

Peripheral vascular diseases

198 (52.5%)

9 (32.1%)

0.059

 

hypertension

22 (5.8%)

3 (10.7%)

0.53

 

Renal failure

27 (7.2%)

4 (14.3%)

0.318

 

Coagulopathy

66 (17.5%)

11 (39.3%)

0.01

 

Fluid and electrolyte disorders

82 (21.8%)

7 (25.0%)

0.87

Laboratory indicators on admission

 

Anion gap (mEq/L)

12.00 [11.00, 14.00]

17.00 [15.75, 22.00]

 < 0.001

 

Bicarbonate (mEq/L)

23.00 [21.00, 25.00]

17.50 [15.75, 21.00]

 < 0.001

 

Creatinine (mg/dL)

1.00 [0.80, 1.20]

1.65 [1.15, 2.10]

 < 0.001

 

Blood urea nitrogen (mg/dL)

17.00 [13.00, 21.00]

27.00 [20.75, 34.25]

 < 0.001

 

Hematocrit (%)

25.00 [21.10, 29.00]

24.65 [21.00, 26.10]

0.266

 

Hemoglobin (g/dL)

8.50 [7.40, 9.80]

8.35 [7.00, 8.80]

0.106

 

PTT (sec)

41.45 [34.35, 51.55]

76.45 [43.55, 122.25]

 < 0.001

 

PT (sec)

15.80 [14.60, 17.50]

17.55 [14.75, 19.40]

0.074

 

INR

1.50 [1.30, 1.70]

1.80 [1.37, 2.32]

0.026

 

white blood cell count

(K/μL)

12.50 [9.90, 15.70]

14.65 [10.38, 16.95]

0.048

 

Platelet count (K/μL)

124.00 [89.75, 156.00]

84.50 [61.00, 120.00]

 < 0.001

Treatment

 

Extracorporeal circulation

243 (64.5%)

7 (25.0%)

 < 0.001

 

Bypass surgery

14 (3.7%)

2 (7.1%)

0.692

 

Ventilation in first day

356 (94.4%)

26 (92.9%)

1

 

Urine output on first day (ml)

2026.00 [1393.50, 3038.75]

948.00 [344.00, 1428.00]

 < 0.001

Severity scores

 

GCS

15.00 [14.25, 15.00]

15.00 [15.00, 15.00]

0.133

 

SOFA

5.00 [4.00, 8.00]

9.00 [7.75, 11.25]

 < 0.001

 

SAPSII

32.00 [26.00, 42.00]

49.50 [43.75, 65.00]

 < 0.001

  1. The continuous data’s normality was tested with Shapiro–Wilk normality test. And in two independent groups compare, continuous variables with normal distribution would be represented by mean with standard deviation (SD), compared with t-test. Continuous variables with abnormal distribution would be represented by median and interquartile range, compared with Wilcoxon rank sum test. Categorical variables would be represented by frequency and percentage, compared with chi-square test. 0.2% of patients had unknown value for hemoglobin; 0.2% for platelet; 2.2% for PTT; 2.2% for PT; 2.2% for INR; 0.5% for white blood cell count; 0.4% for urine output on first day; 0.7% for GCS score. Abbreviation: LOS, length of stay; PTT, partial thromboplastin time; PT, prothrombin time; INR, international normalized ratio; GCS, Glasgow Coma Scale; SOFA, sequential organ failure assessment; SAPSII, simplified acute physiology score II