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Table 2 Laboratory, echocardiographic and electrocardiographic characteristics in patients with AL-CA in the present study

From: A real-world study on diagnosis and prognosis of light-chain cardiac amyloidosis in Southern China

  Normal range AL-CA (n = 170)
Laboratory results
Hemoglobin, g/L 115–150 113.6 (22.7)
White blood cell,10^9/L 3.5–9.5 6.6 (3.0)
Platelets, 109/L 125–350 191.4 (90.7)
Potassium, mmol/L 3.5–5.3 4.1 (0.5)
Calcium, mmol/L 2.11–2.52 2.1 (0.2)
ALT, u/L 7.0–40 19.6 (13.4–28.3)
AST, u/L 13.0–35.0 27.5 (20.3–36.3)
Albumin, g/L 40.0–55.0 29.9 (6.8)
eGFR, mL/(min × 1.73m2) 90–120 60.6 (31.4)
Uric acid, umol/L 155–357 455.5 (168.5)
24-h urine protein ≥ 1.0 g, n% 90 (53.0%)
Cardiac troponin T, pg/ml 0–14 84.8 (36.4–158.8)
CK-MB, u/L 0–24 14.6 (10.2–18.9)
NT-proBNP, pg/mL 100–300 6139.4 (2957.7–11,754.0)
LDH, U/L 120–250 268.6 (216.8–331.5)
CRP, mg/L 0–8 22.6 (39.0)
TC, mmol/L 2.9–5.2 4.1 (2.1)
LDL-c, mmol/L < 3.12 2.6 (1.4)
D-Dimer, ug/mL 0–0.55 1.7 (1.8)
Echocardiographic findings
LVEDd, mm Male: ≤ 55, Female ≤ 50 44.0 (7.1)
RVEDd, mm  ≤ 35 32.5 (4.9)
LAESd, mm Male: ≤ 35, Female ≤ 30 41.0 (7.3)
RAESd, mm ≤ 30 38.4 (8.5)
IVS, mm 6–11 14.1 (3.6)
LVPW, mm 6–11 13.7 (3.3)
LVEF, (%) > 50% 52.9 (10.0)
ECG findings
Atrial fibrillation, n% (164) 29 (17.7%)
AV block grade I or greater, n% (164) 23 (14.0%)
Low voltage, n% (163) 93 (57.1%)
Pseudo necrosis, n% (163) 6 (3.7%)
PRWP, n% (163) 138 (84.7%)
PR interval, ms 120–200 (133) 173.8 (40.8)
Corrected QT interval, ms 320–440 (163) 471.6 (36.7)
QRS duration, ms 60–110 (163) 101.6 (38.0)
Ventricular rate, n/min 60–100 (164) 81.9 (19.6)
  1. Data are (N) Mean (SD) or (N) n (%), Median (Q3–Q1), where N is the total number of patients with available data
  2. ALT: Alanine transaminase; AST: aspartate aminotransferase; eGFR: estimated glomerular filtration rate; CK-MB: creatine kinase myocardial isoenzyme; CRP: C-reactive protein; LDL-C: low density lipoprotein-cholesterol; TC: total cholesterol; LDH: lactate dehydrogenase; NT-proBNP: N-terminal pro–B-type natriuretic peptide; LVEDd: left ventricular end diastolic diameter; RVEDd: right ventricular end diastolic diameter; LAESd: left atrium end systolic diameter; RAEDd: right atrium end systolic diameter; IVS: interventricular septum; LVPW: left ventricular posterior wall; LVEF: left ventricular ejection fraction; PRWP: poor R-wave progression