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Table 2 The changes in study outcomes for all participants at 12 months (N = 111)

From: The impact of antihypertensive treatment initiation on health-related quality of life and cardiovascular risk factor levels: a prospective, interventional study

Outcome

At baseline mean (SD)

Change at 12 months mean (95% CI)

P-value

Office SBP, mmHg

173 (20)

 − 22 (− 27 to − 18)

 < 0.001

Office DBP, mmHg

102 (12)

 − 13 (− 15 to − 10)

 < 0.001

Home SBP, mmHg

153 (13)

 − 15 (− 18 to − 11)

 < 0.001

Home DBP, mmHg

92 (7)

 − 10 (− 12 to − 8)

 < 0.001

EQ-5D

0.872 (0.153)

 − 0.045 (− 0.076 to − 0.015)

0.004

EQ-5D VAS

77 (14)

1 (− 1 to 3)

0.32

Weight, kg

84.1 (17.2)

0.0 (0.7 to 0.7)

0.94

Waist circumference, cm

101 (16)

 − 1 (− 3 to 1)

0.21

Total cholesterol, mmol/l

5.36 (1.11)

 − 0.37 (− 0.56 to − 0.19)

 < 0.001

LDL cholesterol, mmol/l

3.15 (1.01)

 − 0.32 (− 0.51 to − 0.13)

 < 0.001

HDL cholesterol, mmol/l

1.61 (0.45)

 − 0.04 (− 0.08 to 0.01)

0.069

Triglycerides, mmol/l

1.37 (0.98)

 − 0.01 (− 0.13 to 0.10)

0.82

Fasting glucose, mmol/l

5.87(0.85)

 − 0.07 (− 0.23 to 0.10)

0.40

Alcohol use, AUDIT-C score

3.3 (2.6)

 − 0.2 (− 0.5 to − 0.0)

0.048

Physical activity, FIT index

38 (19)

2 (–1 to 5)

0.10

  1. AUDIT-C, alcohol consumption questions from the alcohol use disorders identification test (AUDIT); DBP, diastolic blood pressure, EQ-5D, EuroQoL questionnaire of health-related quality of life; FIT index, Frequency-Intensity-Time (FIT) Index; HDL, high-density lipoprotein; LDL, low-density lipoprotein; SBP, systolic blood pressure; VAS, visual analogue scale