Effect of sodium-glucose cotransporter 2 (SGLT2) inhibitors on left ventricular remodelling and longitudinal strain: a prospective observational study

Table 5 Comparisons between baseline and 6-month variables by repeated-measures ANOVA

Variable	Group (p value)	Time (p value)	Group-time (p value)
Indexed LVM (g/m²)	0.56	0.01	0.04
LV end-diastolic volume (ml)	0.53	0.64	0.81
LV end-diastolic diameter (mm)	0.19	0.48	0.12
LV ejection fraction (%)	0.32	0.79	0.93
RWT	0.35	0.21	0.70
GLS	0.02	0.005	0.04
LA indexed volume (ml/m²)	0.27	0.80	0.60
E/A ratio	0.36	0.74	0.01
Lateral e’ (cm/s)	0.52	0.31	0.42
Septal e’ (cm/s)	0.30	0.03	0.18
E/e’ ratio	0.31	0.16	0.83
Glycated haemoglobin	0.29	< 0.001	0.22

LVM left ventricular mass, LV left ventricular, RWT relative wall thickness, GLS global longitudinal strain, LA left atrial

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