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Table 2 Basal echocardiographic characteristics in SGLT2i and control group

From: Effect of sodium-glucose cotransporter 2 (SGLT2) inhibitors on left ventricular remodelling and longitudinal strain: a prospective observational study

Variable SGLT2i (n = 30) Control (n = 22) p value
LV end-diastolic diameter (mm) 46.9 ± 5.0 44.5 ± 4.3 0.08
LV end-diastolic volume (ml) 103.3 ± 40.0 97.0 ± 25.7 0.52
LV indexed end-diastolic volume (ml/m2) 52.6 ± 18.9 50.2 ± 9.7 0.59
LV end-systolic volume (ml) 40.7 ± 26.5 33.9 ± 8.5 0.19
LV ejection fraction (%) 62.9 ± 8.2 64.6 ± 5.8 0.43
LV ejection fraction < 50% 2 (7%) 0 (0%) 0.50
E wave (cm/s) 72.2 ± 25.5 64.2 ± 19.7 0.22
A wave (cm/s) 82.8 ± 18.9 87.5 ± 19.2 0.41
LA indexed volume (ml/m2) 31.9 ± 9.8 28.7 ± 9.1 0.23
Lateral e’ (cm/s) 8.3 ± 2.2 8.3 ± 3.2 0.95
Septal e’ (cm/s) 5.9 ± 1.4 5.8 ± 1.2 0.73
E/A ratio 0.83 ± 0.39 0.81 ± 0.26 0.80
E/e’ ratio 10.5 ± 3.6 9.8 ± 2.4 0.40
LV indexed mass (g/m2) 98.5 ± 27.9 90.8 ± 21.0 0.28
RWT 0.47 ± 0.07 0.49 ± 0.08 0.29
GLS − 17.8 ± 2.9 − 19.6 ± 2.5 0.02
  1. LV left ventricular, LA left atrial, RWT relative wall thickness, GLS global longitudinal strain