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Table 2 Risk factors of ISR by cox proportional hazard model among study patients undergoing PCI

From: Risk factors of in-stent restenosis among coronary artery disease patients with syphilis undergoing percutaneous coronary intervention: a retrospective study

Variables

Unadjusted

Adjusted

HR (95%CI)

p

HR (95%CI)

p

Age ≥ 50 years

0.88 (0.31–2.47)

0.803

9.09 (0.87–94.63)

0.065

Gender-Male

1.94 (0.44–8.51)

0.378

0.50 (0.04–6.27)

0.594

Smoking history

1.08 (0.38–3.04)

0.888

0.96 (0.06–16.78)

0.979

Alcoholic drinking

2.65 (0.99–7.10)

0.053

4.82 (0.65–35.52)

0.123

Cardiovascular syphilis

1.07 (0.14–8.09)

0.948

4.81 (0.39–59.47)

0.221

Hypertension

0.75 (0.29–1.90)

0.541

0.68 (0.18–2.64)

0.576

Diabetes

1.32 (0.52–3.34)

0.562

1.11 (0.36–3.46)

0.860

Dyslipidemia

2.10 (0.68–6.47)

0.198

1.40 (0.35–5.67)

0.638

HCY ≥ 15umol/L

1.80 (0.70–4.67)

0.227

1.39 (0.40–4.81)

0.606

Titres of TRUST > 1:16

4.58 (1.68–12.47)

0.003

3.72 (1.22–11.36)

0.021

Number of target vessels ≥ 3

2.69 (0.95–7.60)

0.062

2.16 (0.58–8.01)

0.249

Implanted stent numbers > 3

3.31 (1.27–8.66)

0.015

1.92 (0.47–7.86)

0.364

Average stent length ≥ 35 mm

3.49 (1.13–10.75)

0.029

4.47 (1.30–15.44)

0.018

Average stent diameter ≤ 3 mm

3.26 (0.43–24.61)

0.252

1.84 (0.20–17.37)

0.595

Effective DAPT

1.08 (0.39–3.04)

0.881

1.32 (0.34–5.15)

0.694

Successful antisyphilitic treatment

0.08 (0.01–0.61)

0.015

0.12 (0.02–0.95)

0.045

  1. ISR: in-stent restenosis; CAD:coronary artery disease; PCI:percutaneous coronary intervention; HR: Hazard Ratio; HCY:homocysteine; DAPT:dual anti-platelet therapy