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Table 1 Univariate analysis of possible risk factors for POHL after AADS

From: Risk factors and in-hospital mortality of postoperative hyperlactatemia in patients after acute type A aortic dissection surgery

Characteristic

Without POHL

n = 299 (%)

With POHL

n = 188 (%)

P value

Demographics

   

Male

216 (72.2)

152 (80.9)

0.031

Age (years)

49.39 ± 11.63

50.14 ± 10.92

0.477

Body mass index (kg/m2)

25.15 ± 3.80

25.60 ± 3.49

0.182

Smoking history

124 (41.5)

89 (47.3)

0.204

Drinking history

104 (34.8)

70 (37.2)

0.583

Underlying conditions

   

Hypertension

199 (66.6)

133 (70.7)

0.334

Diabetes mellitus

16 (5.4)

5 (2.7)

0.155

Chronic obstructive pulmonary disease

3 (1.0)

2 (1.1)

0.949

Cerebrovascular disease

51 (17.1)

37 (19.7)

0.464

Peripheral vascular disease

40 (13.4)

25 (13.3)

0.980

Renal insufficiency

91 (30.4)

78 (41.5)

0.013

Gastrointestinal tract disease

22 (7.4)

20 (10.6)

0.209

Atrial fibrillation

4 (1.3)

0 (0)

0.304

Surgery history

71 (23.7)

50 (26.6)

0.479

Pulmonary artery hypertension

10 (3.3)

4 (2.1)

0.581

Pericardial effusion

88 (29.4)

42 (22.3)

0.085

Left ventricular ejection fraction (%)

62 (60, 65)

62 (60, 65)

0.945

Laboratory values

   

White blood cell count (× 109/L)

9.8 (7.5, 12.5)

10.4 (7.8, 13.3)

0.228

Red blood cell count (× 1012/L)

4.2 (3.7, 4.5)

4.3 (3.9, 4.6)

0.030

Hemoglobin (g/l)

125 (111, 138)

131 (119, 141)

0.005

Platelet count (× 109/L)

162 (126, 210)

154 (126, 186)

0.120

Serum creatinine (μmol/L)

78.0 (65.2, 109.0)

83.0 (69.0, 115.5)

0.164

Serum albumin (g/L)

37.4 (34.4, 40.7)

38.3 (35.7, 41.0)

0.048

Serum globulin (g/L)

25.7 (22.6, 28.5)

25.3 (23.0, 28.0)

0.625

Operative variables

   

Surgical types

  

0.003

Isolated AADS

209 (69.9)

110 (58.5)

 

Combined valve surgery

68 (22.7)

42 (22.3)

 

Combined coronary artery bypass grafting

9 (3.0)

16 (8.5)

 

Combined valve and coronary surgery

10 (3.3)

16 (8.5)

 

Combined other types of cardiac surgery

3 (1.0)

4 (2.1)

 

Cardiopulmonary bypass time (minutes)

199 (162, 239)

233 (197, 274)

< 0.001

Aortic cross clamp time (minutes)

116 (94, 142)

130 (104, 155)

< 0.001

Transfusion of red blood cells (units)

4 (3, 6)

6 (4, 8)

< 0.001

  1. AADS, Stanford type A acute aortic dissection surgery; POHL, postoperative hyperlactatemia