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Table 5 Logistic regression model analysis of serum Hcy on each index

From: Distribution characteristics and influencing factors of homocyteine in an apparently healthy examined population

 

Single factor analysis

Multiple-factor analysis

OR (95%CI)

P

OR (95%CI)

P

TG < 1.7 mmol/L

    

lnHcy

1.870 (1.581–2.212)

 < 0.001

1.281 (1.078–1.523)

0.005

Hcy (vs. Hcy ≤ 15 μmol/L)

1.285 (0.928–1.780)

0.131

1.116 (0.791–1.573)

0.533

TC < 5.2 mmol/L

    

lnHcy

1.054 (0.911–1.219)

0.479

1.083 (0.929–1.263)

0.307

Hcy (vs. Hcy ≤ 15 μmol/L)

0.795 (0.573–1.104)

0.171

0.743 (0.531–1.041)

0.084

HDL-C > 1.0 mmol/L

    

lnHcy

1.803 (1.404–2.316)

 < 0.001

1.065 (0.835–1.359)

0.613

Hcy (vs. Hcy ≤ 15 μmol/L)

1.772 (1.184–2.653)

0.005

1.558 (1.017–2.386)

0.042

LDL-c < 3.4 mmol/L

    

lnHcy

0.905 (0.776–1.055)

0.201

0.820 (0.699–0.962)

0.015

Hcy (vs. Hcy ≤ 15 μmol/L)

0.859 (0.603–1.225)

0.401

0.819 (0.570–1.177)

0.280

γ-GT (10–60 U/L (7–45 U/L))

    

lnHcy

1.270 (1.028–1.569)

0.027

0.902 (0.729–1.116)

0.343

Hcy (vs. Hcy ≤ 15 μmol/L)

1.186 (0.808–1.740)

0.384

1.108 (0.744–1.649)

0.615

ALT (9–50 U/L (7–40 U/L))

    

lnHcy

0.899 (0.720–1.123)

0.348

0.791 (0.627–0.998)

0.048

Hcy (vs. Hcy ≤ 15 μmol/L)

1.411 (0.880–2.260)

0.153

1.175 (0.717–1.924)

0.522

ALP (45–125 U/L (35–100 U/L))

    

lnHcy

0.692 (0.531–0.900)

0.006

0.726 (0.550–0.958)

0.024

Hcy (vs. Hcy ≤ 15 μmol/L)

1.940 (1.093–3.444)

0.024

1.992 (1.111–3.571)

0.021

TBIL ≤ 23 μmol/L

    

lnHcy

2.456 (1.741–3.464)

 < 0.001

1.707 (1.205–2.418)

0.003

Hcy (vs. Hcy ≤ 15 μmol/L)

1.211 (0.736–1.993)

0.452

1.241 (0.750–2.055)

0.401

Urea (3.1–8.8 mmol/L)

    

lnHcy

1.181 (0.767–1.817)

0.450

1.046 (0.675–1.623)

0.839

Hcy (vs. Hcy ≤ 15 μmol/L)

0.817 (0.367–1.818)

0.620

0.963 (0.433–2.145)

0.927

UA (UA ≤ 420 umol/L(UA ≤ 360umol/L))

    

lnHcy

3.106 (2.439–3.956)

 < 0.001

2.008 (1.565–2.575)

 < 0.001

Hcy (vs. Hcy ≤ 15 μmol/L)

1.485 (1.052–2.096)

0.024

1.487 (1.037–2.131)

0.031

Cr (57–97 μmoI/L (41–73 μmoI/L))

    

lnHcy

0.737 (0.565–0.960)

0.023

0.663 (0.508–0.866)

0.003

Hcy (vs. Hcy ≤ 15 μmol/L)

2.068 (1.271–3.366)

0.003

2.241 (1.364–3.681)

0.001

  1. Multivariate analysis adjusted for age, gender, smoking, drinking, and BMI. LnHcy is the logarithm of Hcy, which is a continuous variable, Hcy is a binary variable, vs. refers to the comparison group, high Hcy > 15 μmol/L vs. low Hcy ≤ 15 μmol/L. The normal reference value ranges of TBIL, Urea, ALP and Cr are indicated by brackets. If there are double brackets, the outer brackets indicate the normal reference value range for men, and the inner brackets indicate the normal reference value range for women. The normal range of Cr and Urea in parentheses indicates the 20–59 years old population, the 60–79 years old population Cr normal range is (57–111 μmoI/L (41–81 μmoI/L)); the 60–79 year old population Urea's normal range is (3.6–9.5 mmol/L (3.1–8.8 mmol/L))
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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