Clinical prediction scores and early anticoagulation therapy for new-onset atrial fibrillation in critical illness: a post-hoc analysis

Table. 3 Estimates of the effect of covariates on hospital mortality or cerebral infarction in the Cox proportional hazards models

	Adjusted hazard ratio (95% CI)	P value
Anticoagulation therapy within 48 h from AF onset	0.77 (0.47–1.23)	0.281
Age (per 5 year old)	1.02 (0.92–1.15)	0.664
Male	1.11 (0.68–1.87)	0.680
APACHE II score (per 5 points)	1.05 (0.91–1.21)	0.490
Infection at AF onset	1.02 (0.60–1.82)	0.950
CHA2DS2-VASc score	1.04 (0.88–1.28)	0.743
HAS-BLED bleeding score	1.13 (0.86–1.47)	0.394
Mechanical ventilation at AF onset	1.24 (0.75–2.13)	0.418
Renal replacement therapy at AF onset	1.98 (1.20–3.27)	0.007

Adjusted by the following factors; age, sex, APACHE II score, CHA2DS2-VASc score, HAS-BLED bleeding score, Mechanical ventilation, Renal replacement therapy, and infection at AF onset
AF, atrial fibrillation; APACHE II, acute physiology and chronic health evaluation II

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