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Table. 1 Patient characteristics: non-early group vs. early group

From: Clinical prediction scores and early anticoagulation therapy for new-onset atrial fibrillation in critical illness: a post-hoc analysis

 

OverallN = 308

Non-early groupN = 213

Early groupN = 95

P value

Age, years

75 (66–82)

74 (66–81)

75 (66–83)

0.495

Male, n (%)

208 (67.5%)

144 (67.6%)

64 (67.4%)

0.967

Body mass index, kg/m2

22.7 (19.6–25.3)

22.5 (19.4–25.3)

22.9 (20.1–25.2)

0.824

Patient category

   

0.699

 Non-scheduled surgery, n (%)

78 (25.3%)

51 (23.9%)

27 (28.4%)

 

 Scheduled surgery, n (%)

36 (11.7%)

25 (11.7%)

11 (11.6%)

 

 Medical, n (%)

194 (63.0%)

137 (64.3%)

57 (60.0%)

 

APACHE II score at ICU admission

24 (19–30)

25 (20–30)

23 (18–27)

0.039

SOFA score at AF onset

8 (6–11)

8 (6–12)

7 (5–9)

0.009

Chronic hemodialysis, n (%)

17 (5.5%)

14 (6.6%)

3 (3.2%)

0.226

CHA2DS2-VASc score

3 (2–4)

3 (2–4)

3 (2–4)

0.859

CHA2DS2-VASc ≥ 2, n (%)

244 (79.2%)

169 (79.3%)

75 (79.0%)

0.937

HAS-BLED bleeding risk score

2 (1–3)

2 (1–3)

2 (1–3)

0.562

 HAS-BLED ≥ 3, n (%)

82 (26.6%)

58 (27.2%)

24 (25.3%)

0.718

Infection at AF onset, n (%)

230 (74.7%)

157 (73.7%)

73 (76.8%)

0.559

From ICU admission to AF onset, hours

28.8 (15.3–113.8)

27.0 (13.9–115.1)

31.5 (15.4–113.8)

0.384

Treatment at AF onset

    

 Mechanical ventilation, n (%)

212 (68.8%)

148 (69.5%)

64 (67.4%)

0.711

 Renal replacement therapy, n (%)

83 (27.0%)

67 (31.5%)

16 (16.8%)

0.008

 Vasopressors, n (%)

157 (51.0%)

107 (50.2%)

50 (52.6%)

0.698

 Inotropes, n (%)

39 (12.7%)

25 (11.7%)

14 (14.7%)

0.465

  1. CHA2DS2-VASc score (Congestive heart failure; Hypertension; Age ≥ 75 years [2 points]; Diabetes; previous Stroke, transient ischemic attack, or thromboembolism [2 points]; Vascular disease; Age 65–74 years; and Female); range 0–9 points. A score ≥ 2 indicates “high risk.” HAS-BLED bleeding score (Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile international normalized ratio, Elderly (> 65 years), Drugs/alcohol concomitantly); range 0–6 points. A score ≥ 3 indicates “high risk”
  2. AF, atrial fibrillation; APACHE II, acute physiology and chronic health evaluation II; ICU, intensive care unit; SOFA, sequential organ failure assessment