Individual and combined association analysis of famine exposure and serum uric acid with hypertension in the mid-aged and older adult: a population-based cross-sectional study

Table 4 Separate associations of famine exposure, SUA levels with prevalence of hypertension (N = 9368)

Variables	Male (OR and 95% CI for hypertension)				Female (OR and 95% CI for hypertension)
Famine exposure	Model one^a	Model two^b	Model three^c	Model four^d	Model one^a	Model two^b	Model three^c	Model four^d
No-exposed	1.00 (reference)	1.00 (reference)	1.00 (reference)	1.00 (reference)	1.00 (reference)	1.00 (reference)	1.00 (reference)	1.00 (reference)
Fetal exposed	1.32 (0.98, 1.77)	1.32 (0.98, 1.77)	1.30 (0.97, 1.75)	1.35 (1.00, 1.82)	1.18 (0.92, 1.52)	1.16 (0.90, 1.49)	1.17 (0.91, 1.51)	1.16 (0.90, 1.51)
Childhood-exposed	1.41 (1.12, 1.79)	1.42 (1.12, 1.79)	1.41 (1.11, 1.79)	1.54 (1.21, 1.96)	1.67 (1.37, 2.03)	1.51 (1.24, 1.85)	1.54 (1.25, 1.88)	1.62 (1.32, 1.99)
Adolescence/adult-exposed	2.06 (1.63, 2.60)	1.98 (1.56, 2.51)	1.99 (1.57, 2.52)	2.38 (1.86, 3.04)	3.61 (2.96, 4.40)	2.98 (2.41, 3.68)	3.04 (2.45, 3.76)	3.46 (2.78, 4.30)
P for trend	< 0.001	< 0.001	< 0.001		< 0.001	< 0.001	< 0.001	< 0.001
SUA levels	Model one^a	Model two^f	Model three^g	Model four^e	Model one^a	Model two^f	Model three^g	Model four^e
Normal	1.00 (reference)	1.00 (reference)	1.00 (reference)	1.00 (reference)	1.00 (reference)	1.00 (reference)	1.00 (reference)	1.00 (reference)
High	1.94 (1.53, 2.47)	1.89 (1.48, 2.42)	1.90 (1.48, 2.42)	1.74 (1.36, 2.23)	2.25 (1.73, 2.93)	1.93 (1.47, 2.53)	1.93 (1.47, 2.54)	1.72 (1.31, 2.27)

Variables	Total (OR and 95% CI for hypertension)
Famine exposure	Model one^a	Model two^b	Model three^c	Model four^d
No-exposed	1.00 (reference)	1.00 (reference)	1.00 (reference)	1.00 (reference)
Fetal exposed	1.25 (1.03, 1.51)	1.24 (1.02, 1.50)	1.24 (1.02, 1.51)	1.25 (1.03, 1.52)
Childhood-exposed	1.56 (1.34, 1.81)	1.48 (1.27, 1.73)	1.50 (1.29, 1.75)	1.60 (1.37, 1.87)
Adolescence/adult-exposed	2.77 (2.38, 3.22)	2.44 (2.09, 2.84)	2.46 (2.10, 2.87)	2.87 (2.44, 3.37)
P for trend	< 0.001	< 0.001	< 0.001	< 0.001
SUA levels	Model one^a	Model two^f	Model three^g	Model four^e
Normal	1.00 (reference)	1.00 (reference)	1.00 (reference)	1.00 (reference)
High	2.06 (1.73, 2.46)	1.91 (1.59, 2.29)	1.91 (1.60, 2.29)	1.73 (1.44, 2.08)

BMI, body mass index; CI, confidence interval; OR, odds ratios; SUA, serum uric acid; SBP, systolic blood pressure
(1) In model one, ^aUnadjusted, age-adjusted by design;
(2) In model two: ^bAdjusted for age, education, marital status, living place, and SUA; ^f Adjusted for age, education, marital status, living place, and famine exposure
(3) In model three: ^cAdjusted for age, education, marital status, living place, smoking status, alcohol consumption status, eating habit, social and leisure activities, experience of a traumatic event, taking physical activity or exercise, and SUA; ^gAdjusted for age, education, marital status, living place, smoking status, alcohol consumption status, eating habit, social and leisure activities, experience of a traumatic event, taking physical activity or exercise, and famine exposure
(4) In model four: ^dAdjusted for age, education, marital status, living place, smoking status, alcohol consumption status, eating habit, social and leisure activities, experience of a traumatic event, taking physical activity or exercise, BMI, and SUA; ^eAdjusted for age, education, marital status, living place, smoking status, alcohol consumption status, eating habit, social and leisure activities, experience of a traumatic event, taking physical activity or exercise, BMI, and famine exposure

ISSN: 1471-2261