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Table 4 Sex stratified incidence rates and hazard ratios for emergency department visit or hospitalization for acute coronary syndrome or stroke and for any cardiovascular event among patients with medical cannabis authorisation and non-authorized controls

From: Medical cannabis authorization and the risk of cardiovascular events: a longitudinal cohort study

  

Primary outcome: acute coronary syndrome or stroke

Secondary outcome: any cardiovascular event

Sex

Exposure group

Number of events

Total person-years

Incidence rate per 1000 persons-years (95% CI)

Adjusted Hazard ratio (95% CI)*

Number of events

Total person-years

Incidence rate per 1000 persons-years (95% CI)

Adjusted Hazard ratio (95% CI)*

Males

Authorized to use cannabis

69

7896.50

8.73 (6.91–11.05)

1.77 (1.23–2.56)

233

7819.88

29.79 (26.25–33.81)

1.52(1.24–1.86)

Controls

132

21,496.29

6.14 (5.18–7.28)

1 [Reference]

416

21,341.38

19.49 (17.72–1.44)

1 [Reference]

Females

Authorized to use cannabis

33

6290.18

5.25 (3.73–7.37)

0.98 (0.59–1.62)

165

6220.11

26.53 (22.82–30.84)

1.41(1.11 -1.79)

Controls

91

17,846.26

5.10 (4.15–6.26)

1 [Reference]

326

17,702.85

18.41 (16.54–20.51)

1 [Reference]

  1. *Conditional Cox model further adjusted for history of any CV and area of living