From: Medical cannabis authorization and the risk of cardiovascular events: a longitudinal cohort study
Primary outcome: acute coronary syndrome or stroke | Secondary outcome: any cardiovascular event | ||||||||
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Sex | Exposure group | Number of events | Total person-years | Incidence rate per 1000 persons-years (95% CI) | Adjusted Hazard ratio (95% CI)* | Number of events | Total person-years | Incidence rate per 1000 persons-years (95% CI) | Adjusted Hazard ratio (95% CI)* |
Males | Authorized to use cannabis | 69 | 7896.50 | 8.73 (6.91–11.05) | 1.77 (1.23–2.56) | 233 | 7819.88 | 29.79 (26.25–33.81) | 1.52(1.24–1.86) |
Controls | 132 | 21,496.29 | 6.14 (5.18–7.28) | 1 [Reference] | 416 | 21,341.38 | 19.49 (17.72–1.44) | 1 [Reference] | |
Females | Authorized to use cannabis | 33 | 6290.18 | 5.25 (3.73–7.37) | 0.98 (0.59–1.62) | 165 | 6220.11 | 26.53 (22.82–30.84) | 1.41(1.11 -1.79) |
Controls | 91 | 17,846.26 | 5.10 (4.15–6.26) | 1 [Reference] | 326 | 17,702.85 | 18.41 (16.54–20.51) | 1 [Reference] |