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Table 2 Baseline characteristics based on CA-125 quartiles

From: Plasma carbohydrate antigen-125 for prediction of atrial fibrillation recurrence after radiofrequency catheter ablation

Characteristics

CA-125 level

P-value

Quartile 1

Quartile 2

Quartile 3

Quartile 4

(n = 87)

(n = 90)

(n = 88)

(n = 88)

General clinical characteristics

Age (years)

62.23 ± 8.87

61.78 ± 9.20

60.14 ± 10.58

62.08 ± 9.13

0.469

Sex

    

0.957

 Male

51 (58.6)

51 (56.7)

48 (54.5)

49 (55.7)

 

 Female

36 (41.4)

39 (43.3)

40 (45.5)

39 (44.3)

 

BMI (kg/m2)

24.81 ± 3.10

24.86 ± 2.99

25.12 ± 3.34

24.33 ± 2.93

0.395

SBP (mmHg)

127.79 ± 14.82

131.12 ± 15.46

127.02 ± 16.10

126.40 ± 14.89

0.170

DBP (mmHg)

78.34 ± 10.61

79.82 ± 10.42

80.30 ± 9.69

78.23 ± 10.61

0.443

Type of AF

    

0.085

 Paroxysmal

69 (79.3)

64 (71.1)

68 (77.3)

56 (63.6)

 

 Persistent

18 (20.7)

26 (28.9)

20 (22.7)

32 (36.4)

 

AF duration (months)

20.67 ± 43.62

21.56 ± 31.52

27.66 ± 32.84

31.17 ± 37.31

0.044

CHADS2 score

0.89 ± 0.81

0.82 ± 0.97

0.91 ± 0.78

1.00 ± 1.12

0.587

CHA2DS2-VASc score

1.77 ± 1.15

1.66 ± 1.42

1.76 ± 1.25

1.94 ± 1.61

0.629

Comorbidity

Hypertension

50 (57.5)

48 (53.3)

59 (67.0)

51 (58.0)

0.299

Diabetes

8 (9.2)

8 (8.9)

6 (6.8)

12 (13.6)

0.476

Dyslipidemia

3 (3.4)

1 (1.1)

7 (8.0)

7 (8.0)

0.073

Stroke/TIA

7 (8.0)

5 (5.6)

3 (3.4)

6 (6.8)

0.606

Hematological index

Hb (g/L)

137.67 ± 16.81

137.87 ± 16.19

138.90 ± 15.71

140.35 ± 16.18

0.681

FBG (mmol/L)

5.00 ± 0.72

5.06 ± 0.82

5.10 ± 0.87

5.15 ± 0.89

0.847

Scr (μmol/L)

69.22 ± 13.31

71.12 ± 16.23

70.38 ± 17.16

69.66 ± 15.58

0.948

UA (μmol/L)

343.58 ± 72.31

333.58 ± 87.98

352.57 ± 100.61

359.00 ± 89.26

0.245

ALB (g/L)

41.83 ± 3.35

42.45 ± 2.92

42.93 ± 3.27

42.09 ± 4.05

0.165

TC (mmol/L)

4.27 ± 0.94

4.32 ± 0.89

4.45 ± 0.93

4.58 ± 1.03

0.141

TG (mmol/L)

1.56 ± 1.34

1.51 ± 0.93

1.57 ± 0.71

1.85 ± 1.24

0.117

LDL-C (mmol/L)

2.47 ± 0.83

2.53 ± 0.78

2.63 ± 0.82

2.60 ± 0.87

0.475

HDL-C (mmol/L)

1.16 ± 0.27

1.13 ± 0.28

1.15 ± 0.28

1.15 ± 0.33

0.810

Echocardiographic parameter

LAD (mm)

41.70 ± 4.71

42.19 ± 5.67

42.22 ± 5.37

43.80 ± 6.01

0.049

LVEF (%)

63.91 ± 5.58

62.62 ± 5.47

63.08 ± 5.33

61.75 ± 5.41

0.068

LVD (mm)

48.71 ± 4.02

49.08 ± 4.46

48.33 ± 4.08

48.76 ± 5.21

0.740

LVS (mm)

31.67 ± 3.78

32.40 ± 4.32

31.74 ± 3.58

32.31 ± 4.32

0.500

Ablation procedure

   

0.230

CPVI alone

58 (66.7)

59 (65.6)

64 (72.7)

51 (58.0)

 

CPVI plus additional ablation

29 (33.3)

31 (34.4)

24 (27.3)

37 (42.0)

 

Direct current cardioversion

22 (25.3)

26 (28.9)

26 (29.5)

29 (33.0)

0.740

Medication

Oral anticoagulant

   

0.999

 Warfarin

6 (6.9)

7 (7.8)

6 (6.8)

6 (6.8)

 

 Dabigatran

63 (72.4)

65 (72.2)

65 (73.9)

62 (70.5)

 

 Rivaroxaban

18 (20.7)

18 (20.0)

17 (23.3)

20 (22.7)

 

ACEI/ARB

32 (36.8)

30 (33.3)

42 (47.7)

41 (46.6)

0.132

β-blocker

40 (46.0)

39 (43.3)

39 (44.3)

47 (53.4)

0.528

Amiodarone

58 (66.7)

62 (68.9)

62 (70.5)

67 (76.1)

0.557

Propafenone

14 (16.1)

16 (17.8)

10 (11.4)

12 (13.6)

0.643

Biomarker

hs-CRP (mg/L)

1.90 ± 1.94

1.23 ± 1.26

1.88 ± 2.75

2.87 ± 3.54

0.001