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Table 3 Baseline characteristics of AAA patients based on different TLR4 and MMP9 expression in situ

From: The elevated expression of TLR4 and MMP9 in human abdominal aortic aneurysm tissues and its implication

Variables TLR4 MMP9
Low (n = 27) High (n = 13) P value Low (n = 19) High (n = 21) P value
Age, years 61.56 ± 8.12 59.00 ± 7.87 0.352 62.00 ± 9.24 59.57 ± 6.77 0.279
Male, n (%) 23 (85.2%) 10 (76.9%) 0.408 16 (84.2%) 17 (81.0%) 0.559
BMI, kg/m2 22.79 ± 2.09 21.32 ± 2.16 0.071 22.68 ± 2.37 22.72 ± 3.12 0.258
Smoking, n (%) 4 (14.8%) 7 (53.8%) 0.015 2 (10.5%) 9 (42.9%) 0.025
Drinking, n (%) 4 (14.8%) 4 (30.8%) 0.221 3 (15.8%) 5 (23.8%) 0.408
Hypertension, n (%) 20 (74.1%) 9 (69.2%) 0.514 14 (73.7%) 15 (71.4%) 0.578
Diabetes, n (%) 7 (25.9%) 3 (23.1%) 0.586 5 (26.3%) 5 (23.8%) 0.571
Dyslipidemia, n (%) 15 (55.6%) 7 (53.8%) 0.711 10 (52.6%) 12 (57.1%) 0.530
WBC, × 109/L 7.74 ± 3.78 10.16 ± 5.24 0.104 7.89 ± 3.75 9.11 ± 4.92 0.417
Hemoglobin, g/dl 129.70 ± 24.17 119.00 ± 30.95 0.239 130.47 ± 21.25 122.38 ± 30.75 0.312
Platelets, × 109/L 216.59 ± 82.05 251.08 ± 103.42 0.260 207.63 ± 76.35 246.05 ± 98.52 0.396
Serum creatinine, μmol/L 79.56 ± 32.38 70.62 ± 39.07 0.449 77.63 ± 36.51 75.76 ± 33.36 0.941
CRP, mg/L 42.93 ± 60.27 82.57 ± 96.68 0.138 38.52 ± 56.93 73.99 ± 88.82 0.132
D-dimer, ug/mL 3.91 ± 4.93 5.85 ± 6.30 0.292 3.546 ± 4.36 5.44 ± 6.17 0.245
Hcy, umol/L 14.21 ± 5.45 14.69 ± 11.00 0.878 15.02 ± 5.39 13.79 ± 9.04 0.672
Cys-c, mg/L 1.05 ± 0.50 0.93 ± 0.31 0.471 1.05 ± 0.58 0.97 ± 0.28 0.599
Family history of AAA, n (%) 2 (7.4%) 1 (7.7%) 0.704 1 (5.3%) 2 (9.5%) 0.538
Max. aortic diameter, cm 5.97 ± 2.10 6.32 ± 2.05 0.667 6.37 ± 2.34 5.79 ± 1.75 0.436
> 5.5 cm, n (%) 8 (29.6%) 9 (69.2%) 0.022 8 (42.1%) 9 (42.9%) 0.500
≤ 5.5 cm, n (%) 16 (59.3%) 3 (23.1%)   10 (52.6%) 9 (42.9%)  
Missing, n (%) 3 (11.1%) 1 (7.7%)   1 (5.3%) 3 (14.3%)  
Max. aortic area, cm2 22.38 ± 14.60 27.71 ± 15.84 0.389 25.89 ± 17.61 23.52 ± 13.68 0.801
Thrombus within AAA
Yes, n (%) 10 (37.0%) 7 (53.8%) 0.200 5 (26.3%) 12 (57.1%) 0.013
No, n (%) 14 (51.9%) 4 (30.8%)   13 (68.4%) 5 (23.8%)  
Missing, n (%) 3 (11.1%) 2 (15.4%)   1 (5.3%) 4 (19.0%)