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Table 1 Clinical demography characteristics, routine and advanced lipids

From: Particles and corrected particles of LDL and non-HDL are stronger predicters of coronary lesion in postmenopausal women

 

Non-CHD group (n = 58)

CHD group (n = 242)

T/χ2

P

Age, y

58.86 ± 8.03

65.76 ± 8.46

5.628

 < 0.001

Smoking, No

7 (12.07%)

18 (7.44%)

1.708

0.252

Overweight a, No

19 (32.76%)

65 (26.86%)

1.327

0.369

Diabetes, No

19 (32.76%)

104 (42.98%)

2.022

0.155

Hypertension, No

34 (58.62%)

143 (59.09%)

0.981

0.948

Family history b, No

11 (18.97%)

37 (15.29%)

1.297

0.493

TIMI Flow 0-I c, No

0 (0.00%)

32 (13.22%)

8.585

0.003

TG (mg/dL)*

133.92 (106.85, 200.46)

148.82 (100.94, 209.08)

0.394

0.694

ApoA1 (mg/dL)

134.31 ± 15.94

130.41 ± 15.74

1.693

0.092

ApoB (mg/dL)*

77.91 (58.51, 89.86)

82.10 (68.75, 98.49)

2.839

0.005

TC-p (nmol/L)*

1416.58 (1063.81, 1633.81)

1492.63 (1250.06, 1790.84)

2.839

0.005

TC (mg/dL)

168.16 ± 38.43

177.74 ± 38.68

1.696

0.091

Lp(a)-p (nmol/L)*

42.80 (16.35, 93.88)

36.40 (13.40, 80.00)

0.801

0.424

Lp(a) (mg/dL)*

17.83 (6.81, 39.12)

14.96 (5.42, 33.12)

0.801

0.424

LDL-p (nmol/L)

1042.17 ± 360.58

1168.91 ± 366.35

2.374

0.018

LDL-C (mg/dL)

81.15 ± 32.77

87.30 ± 30.60

1.354

0.177

LDL-size (nm)*

20.44 (20.23, 20.68)

20.37 (20.17, 20.61)

1.634

0.103

LDL-p-corr (nmol/L)

977.50 ± 357.33

1108.44 ± 366.46

2.456

0.015

LDL-C-corr (mg/dL)

73.10 ± 32.30

79.76 ± 30.41

1.481

0.140

HDL-p (nmol/L)*

73.35 (45.78, 121.62)

78.87 (51.55, 114.60)

0.747

0.455

HDL-C (mg/dL)*

45.81 (38.86, 55.28)

45.23 (40.46, 50.51)

0.877

0.381

Non-HDL-p (nmol/L)

1300.29 ± 381.68

1463.23 ± 424.55

2.675

0.008

Non-HDL-p-corr (nmol/L)

1235.62 ± 377.88

1402.76 ± 426.11

2.740

0.007

Non-HDL-C (mg/dL)

120.62 ± 34.74

131.50 ± 37.68

2.004

0.046

Non-HDL-C-corr (mg/dL)*

112.53 (84.79, 136.45)

116.96 (96.00, 147.17)

2.148

0.033

  1. TG, triglyceride; ApoA1, apolipoprotein A1; ApoB, apolipoprotein B; TC-p, total particles of cholesterol; TC, total cholesterol; Lp(a), lipoprotein a; Lp(a)-p, particles of Lp(a); LDL-C, low-density lipoprotein cholesterol; LDL-p, particles of LDL; LDL-size, average diameter of LDL-p; LDL-p-corr and LDL-C-corr, corrected LDL-p and LDL-C; HDL-C, high-density lipoprotein cholesterol; HDL-p, particles of HDL; non-HDL-C, none high-density lipoprotein cholesterol; non-HDL-p, particles of non-HDL; non-HDL-p-corr and non-HDL-C-corr, corrected non-HDL-p and non-HDL-C
  2. Lp(a) = Lp(a)-p*0.4167; LDL-p-corr = LDL-p – Lp(a)-p; LDL-C-corr = LDL-C – 0.3*Lp(a); non-HDL-p = TC-p – HDL-p; non-HDL-p-corr = non-HDL-p – Lp(a)-p; Non-HDL-C = TC – HDL-C; non-HDL-C-corr = non-HDL-C – 0.3*Lp(a)
  3. TG, ApoB, TC-p, Lp(a)-p, Lp(a), LDL-C-size, HDL-C-p, HDL-C and non-HDL-C-corr were skew distribution and shown as median (25th percentile, 75th percentile). Before the Student’s t-test for the difference between groups, the nonnormal distribution variables were converted into natural logarithm form
  4. aOverweight was defined as body mass index (BMI) > 28 (BMI = weight (Kg) / height (m))
  5. bFamily history was defined as the age of onset of coronary heart disease less than 55 for men and less than 65 for women, in the immediate family members of patients
  6. cTIMI flow classification was used to evaluate coronary artery perfusion by coronary angiography. It was divided into grade 0 (no perfusion); Grade 1 (infiltration without perfusion); Grade 2 (partial perfusion) and Grade 3 (complete perfusion)