Fig. 2

Observed inflammatory and innate antiviral system gene expression contrast between patients with favorable versus unfavorable outcomes after TAVR. The composite gene expression of the 19 pre-specified pro-inflammatory genes was significantly greater in the unfavorable as compared to the favorable outcome group (0.205 log2 RNA ± SE 0.07, p < 0.01). There was no significant difference in composite gene expression of the 34 pre-specified Type 1 interferon genes (0.241 log2 RNA ± SE 0.17, p = 0.18). TAVR = transcatheter aortic valve replacement