Table 1 Baseline characteristics of the study population
Variables | HOCM with AF (N = 105) | HOCM without AF (N = 315) | P |
|---|---|---|---|
Male (N, %) | 62 (59.0) | 188 (59.7) | 0.909 |
Age (y) | 50.7 ± 11.3 | 50.4 ± 11.2 | 0.779 |
BMI (kg/m2) | 25.8 ± 3.9 | 25.6 ± 4.2 | 0.630 |
Heart rate (beats/min) | 73.3 ± 14.0 | 71.8 ± 10.1 | 0.303 |
Systolic blood pressure (mmHg) | 120.6 ± 14.6 | 122.8 ± 15.2 | 0.190 |
Diastolic blood pressure (mmHg) | 72.7 ± 8.8 | 73.3 ± 9.3 | 0.573 |
Smoking (N, %) | 39 (37.1) | 122 (38.7) | 0.840 |
NYHA class | 2.65 ± 0.7 | 2.69 ± 0.5 | 0.329 |
Family history of HCM or SCD (N, %) | 11 (10.5) | 29 (9.2) | 0.701 |
History of cerebrovascular disease (N, %) | 9 (8.6) | 6 (1.9) | 0.001 |
Concomitant disease | |||
MB (N, %) | 20 (19.0) | 23 (7.3) | 0.001 |
PH (N, %) | 19 (18.1) | 25 (7.9) | 0.003 |
Hypertension (N, %) | 27 (25.7) | 94 (29.8) | 0.419 |
Diabetes (N, %) | 7 (6.7) | 17 (5.4) | 0.627 |
Hyperlipemia (N, %) | 41 (39.0) | 79 (25.1) | 0.005 |
Clinic presentation | |||
Chest pain (N, %) | 39 (37.1) | 123 (39.0) | 0.779 |
Amaurosis (N, %) | 12 (11.4) | 69 (21.9) | 0.018 |
Palpitation (N, %) | 51 (48.6) | 63 (20.0) | 0.000 |
Syncope (N, %) | 18 (17.1) | 73 (23.2) | 0.194 |
Echocardiographic indices | |||
Left atrial diameter (mm) | 49.9 ± 7.2 | 45.3 ± 7.0 | 0.000 |
LVEDD (mm) | 42.3 ± 4.9 | 43.0 ± 4.8 | 0.198 |
IVST (mm) | 20.4 ± 5.1 | 19.2 ± 4.5 | 0.024 |
LVOT gradient (mm Hg) | 77.9 ± 25.1 | 84.7 ± 28.1 | 0.028 |
LVEF (%) | 70.1 ± 6.3 | 70.0 ± 7.1 | 0.961 |
Moderate or severe MR (N, %) | 44 (41.9) | 140 (44.4) | 0.650 |