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Table 2 Logistic regression analyses for any increases in eGFR

From: Renoprotective effects of sodium glucose cotransporter 2 inhibitors in type 2 diabetes patients with decompensated heart failure

Variables

All patients (N = 40)

Univariate analysis

Multivariate analysis

95% CI

Odds ratio

p value

95% CI

Odds ratio

p value

Age

0.154

   

Male

0.912

   

Body mass index

0.99–1.39

1.17

0.041

0.265

Systolic blood pressure

0.145

   

Heart rate

0.671

   

HbA1c

0.520

   

Fasting blood sugar

0.311

   

Left ventricular ejection fraction

0.797

   

Ischemic etiology

0.816

   

Atrial fibrillation

0.869

   

Hemoglobin

0.199

   

Hematocrit

0.176

   

Serum albumin

0.068

   

Serum sodium

0.062

   

Serum potassium

0.685

   

eGFR

0.897

   

BNP (per 163 pg/mL increase)

0.16–0.88

0.37

0.016

0.08–0.79

0.26

0.007

NT-proBNP

0.163

   

Beta–blockers

0.100

   

ACEI/ARB

NA

NA

0.009

NA

NA

0.002

Loop diuretics

0.370

   

Furosemide (per 10 mg/day increase)

0.077

   

MRA

0.696

   

Thiazides

0.182

   

Statin

0.704

   

Sulfonylureas

0.950

   

DPP-4i

0.507

   

Biguanides

0.869

   

Insulin

NA

NA

0.030

0.103

  1. HbA1c, glycated hemoglobin; eGFR, estimated glomerular filtration rate; BNP, b-type natriuretic peptide; NT-proBNP, N-terminal pro-b-type natriuretic peptide; ACEI, angiotensin converting enzyme inhibitors; ARB, angiotensin receptor blockers; MRA, mineralocorticoid receptor antagonists; DPP-4i, dipeptidyl peptidase-4 inhibitors
  2. Odds ratio were not calculated in several variables due to statistical divergence