Total (N = 40) | Increased eGFR (N = 26) | No-increased eGFR (N = 14) | P value | |
---|---|---|---|---|
Age, years | 68 (57–75) | 68 (55–72) | 71 (61–79) | 0.177 |
Male, N | 29 (73) | 19 (73) | 10 (71) | 0.911 |
Body weight, kg | 62 (51–73) | 66 (54–76) | 54 (47–71) | 0.112 |
Body mass index, kg/m2 | 23.9 (19.6–27.2) | 24.7 (21.9–27.9) | 20.4 (19.0–24.9) | 0.076 |
Systolic blood pressure, mmHg | 108 (95–119) | 110 (100–119) | 100 (90–120) | 0.173 |
Heart rate, beats per minutes | 70 (63–81) | 69 (63–83) | 74 (64–79) | 0.570 |
HbA1c, % | 6.8 (6.6–7.6) | 6.7 (6.6–7.7) | 7.0 (6.6–7.2) | 0.776 |
Fasting blood sugar, mg/dL | 110 (96–129) | 102 (86–128) | 122 (107–130) | 0.076 |
Left ventricular ejection fraction, % | 42 (27–56) | 39 (28–58) | 42 (26–55) | 0.966 |
Ischemic etiology, N | 19 (48) | 12 (46) | 7 (50) | 0.816 |
Atrial fibrillation, N | 8 (20) | 5 (19) | 3 (21) | 0.868 |
Hemoglobin, g/dL | 12.9 (11.5–15.6) | 13.6 (16.0–11.7) | 12.4 (11.1–14.2) | 0.223 |
Hematocrit, % | 38.5 (34.2–44.9) | 40.6 (35.2–45.6) | 37.6 (33.5–41.4) | 0.192 |
Serum albumin, g/dL | 3.7 (3.5–3.8) | 3.7 (3.5–3.9) | 3.6 (3.2–3.7) | 0.107 |
Serum sodium, mEq/L | 138 (136.3–140) | 139.5 (137.8–140) | 137 (134.5–140.3) | 0.094 |
Serum potassium, mEq/L | 4.4 (4.1–4.6) | 4.4 (4.1–4.6) | 4.4 (4.2–4.5) | 0.943 |
eGFR, mL/minute/1.73m2 | 53.0 (36.1–74.5) | 54.5 (40.0–73.5) | 50.1 (31.6–80.4) | 0.712 |
Plasma BNP, pg/mL | 94 (54–251) | 86 (50–175) | 205 (75–374) | 0.059 |
Plasma NT-proBNP, pg/mL | 864 (260–1819) | 740 (251–1424) | 1479 (356–3057) | 0.242 |
Heart failure therapies | ||||
Beta-blockers, N | 37 (93) | 23 (89) | 14 (100) | 0.186 |
ACEI/ARB, N | 37 (93) | 26 (100) | 11 (79) | 0.014 |
Loop diuretics, N | 19 (48) | 11 (42) | 8 (57) | 0.370 |
Furosemide, mg/day | 0 (0–20) | 0 (0–20) | 20 (0–40) | 0.158 |
MRA, N | 27 (68) | 17 (65) | 10 (71) | 0.697 |
Thiazides, N | 2 (5) | 2 (8) | 0 (0) | 0.287 |
Statin, N | 30 (75) | 20 (77) | 10 (71) | 0.702 |
Anti-diabetic agents | ||||
Sulfonylureas, N | 3 (8) | 2 (8) | 1 (7) | 0.950 |
DPP-4i, N | 20 (50) | 14 (54) | 6 (43) | 0.741 |
Biguanides, N | 8 (20) | 5 (19) | 3 (21) | 0.868 |
Insulin, N | 5 (12) | 5 (19) | 0 (0) | 0.079 |