From: Current status and etiology of valvular heart disease in China: a population-based survey
Characters | Number | VHD | MS | MR | AS | AR |
---|---|---|---|---|---|---|
Total | 31,499 | 3.8 (2.6–5.6) | 0.8 (0.5–1.3) | 1.1 (0.7–1.7) | 0.7 (0.4–1.1) | 1.2 (0.7–2.1) |
Gender | ||||||
 Male | 14,470 | 3.6 (2.5–5.2) | 0.8 (0.4–1.6) | 1.0 (0.7–1.4) | 0.8 (0.4–1.4) | 1.3 (0.8–2.2) |
 Female | 17,029 | 4.0 (2.6–6.1) | 0.8 (0.5–1.3) | 1.2 (0.7–2.1) | 0.6 (0.3–1.0) | 1.2 (0.7–2.0) |
P | Â | 0.308 | 0.967 | 0.096 | 0.194 | 0.459 |
Age (years) | ||||||
 35–44 | 6849 | 1.9 (1.1–3.2) | 0.7 (0.3–1.5) | 0.4 (0.2–0.7) | 0.4 (0.2–0.7) | 0.3 (0.1–0.8) |
 45–54 | 7406 | 2.1 (1.4–3.0) | 0.5 (0.3–1.0) | 0.7 (0.5–1.0) | 0.3 (0.1–0.8) | 0.4 (0.3–0.8) |
 55–64 | 6765 | 4.5 (3.0–6.8) | 0.7 (0.4–1.2) | 1.5 (0.9–2.4) | 0.5 (0.3–1.0) | 1.4 (0.8–2.6) |
 65–74 | 6406 | 7.6 (5.1–11.2) | 1.4 (0.7–2.5) | 2.1 (1.3–3.3) | 1.5 (0.8–2.8) | 3.1 (1.7–5.7) |
 75- | 4073 | 15.9 (10.3–23.7) | 2.1 (1.1–3.8) | 5.2 (3.2–8.3) | 3.4 (1.7–6.7) | 7.1 (4.0–12.3) |
P |  | < 0.001 | 0.002 | < 0.001 | < 0.001 | < 0.001 |
BMI (Kg/m2) | ||||||
 < 18.5 | 1319 | 6.2 (3.7–10.4) | 1.6 (0.6–4.7) | 1.7 (0.6–4.4) | 0.7 (0.2–1.8) | 3.1 (1.6–6.1) |
 18.5–23.9 | 13,036 | 4.0 (2.6–6.0) | 0.7 (0.4–1.4) | 1.2 (0.8–1.8) | 0.7 (0.3–1.3) | 1.2 (0.6–2.1) |
 24–27.9 | 12,042 | 3.7 (2.4–5.5) | 0.8 (0.5–1.3) | 1.1 (0.6–1.9) | 0.7 (0.4–1.1) | 1.2 (0.7–1.9) |
 28- | 5102 | 3.1 (1.9–5.0) | 0.9 (0.5–1.5) | 0.9 (0.5–1.5) | 0.6 (0.3–1.4) | 1.1 (0.6–2.0) |
P | Â | 0.042 | 0.286 | 0.583 | 0.996 | 0.001 |
Region | ||||||
 East | 14,009 | 4.2 (2.5–7.1) | 0.9 (0.5–1.8) | 1.0 (0.6–1.5) | 0.8 (0.4–1.6) | 1.8 (1.0–3.3) |
 Central | 11,895 | 2.4 (1.0–5.9) | 0.4 (0.1–0.9) | 1.1 (0.4–2.9) | 0.2 (0.1–0.6) | 0.6 (0.2–2.1) |
 West | 5595 | 5.2 (2.8–9.5) | 1.2 (0.4–4.3) | 1.4 (0.5–3.9) | 1.1 (0.3–3.5) | 1.1 (0.6–2.0) |
P | Â | 0.134 | 0.070 | 0.800 | 0.022 | 0.022 |
Residence | ||||||
 Rural | 15,009 | 4.5 (2.5–7.9) | 0.9 (0.4–1.9) | 1.3 (0.7–2.4) | 0.8 (0.4–1.6) | 1.4 (0.7–2.9) |
 Urban | 16,490 | 3.4 (2.0–5.6) | 0.7 (0.4–1.5) | 1.0 (0.6–1.7) | 0.6 (0.3–1.3) | 1.1 (0.5–2.3) |
P | Â | 0.407 | 0.636 | 0.551 | 0.603 | 0.629 |
Hypertension | ||||||
 No | 18,163 | 2.8 (1.9–4.2) | 0.6 (0.4–1.1) | 0.8 (0.5–1.3) | 0.4 (0.2–0.6) | 0.7 (0.4–1.2) |
 Yes | 13,336 | 5.6 (3.8–8.3) | 1.1 (0.7–1.8) | 1.6 (1.0–2.4) | 1.2 (0.6–2.3) | 2.2 (1.3–3.6) |
P |  | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
Dyslipidemia | ||||||
 No | 21,830 | 4.0 (2.7–5.9) | 0.8 (0.5–1.4) | 1.1 (0.8–1.7) | 0.7 (0.4–1.1) | 1.3 (0.8–2.2) |
 Yes | 9669 | 3.4 (2.2–5.1) | 0.7 (0.4–1.3) | 1.0 (0.6–1.8) | 0.6 (0.3–1.2) | 1.0 (0.6–1.8) |
P | Â | 0.015 | 0.700 | 0.549 | 0.791 | 0.025 |
Diabetes | ||||||
 No | 28,214 | 3.8 (2.6–5.6) | 0.8 (0.5–1.3) | 1.1 (0.7–1.6) | 0.6 (0.4–1.0) | 1.2 (0.7–2.1) |
 Yes | 3285 | 4.0 (2.5–6.3) | 1.0 (0.6–1.9) | 1.5 (0.8–2.9) | 1.2 (0.5–2.6) | 1.3 (0.7–2.2) |
P | Â | 0.581 | 0.310 | 0.131 | 0.018 | 0.889 |
Stroke | ||||||
 No | 30,656 | 3.7 (2.5–5.5) | 0.8 (0.5–1.3) | 1.1 (0.7–1.7) | 0.6 (0.4–1.1) | 1.2 (0.7–2.0) |
 Yes | 843 | 7.9 (4.0–15.1) | 1.3 (0.4–3.8) | 1.9 (0.8–4.7) | 1.8 (0.7–4.6) | 4.1 (2.2–7.8) |
P |  | 0.004 | 0.295 | 0.185 | 0.003 | < 0.001 |
CKD | ||||||
 No | 29,453 | 3.5 (2.4–5.2) | 0.7 (0.4–1.2) | 1.0 (0.7–1.5) | 0.6 (0.4–1.0) | 1.1 (0.7–1.9) |
 Yes | 2046 | 9.2 (6.0–13.9) | 2.3 (1.3–4.0) | 3.0 (1.7–5.1) | 1.6 (0.7–3.5) | 3.2 (1.5–6.5) |
P |  | < 0.001 | < 0.001 | < 0.001 | 0.001 | < 0.001 |