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Table 2 Prevalence of valvular heart diseases (VHD) in the left heart according to characteristics

From: Current status and etiology of valvular heart disease in China: a population-based survey

Characters

Number

VHD

MS

MR

AS

AR

Total

31,499

3.8 (2.6–5.6)

0.8 (0.5–1.3)

1.1 (0.7–1.7)

0.7 (0.4–1.1)

1.2 (0.7–2.1)

Gender

 Male

14,470

3.6 (2.5–5.2)

0.8 (0.4–1.6)

1.0 (0.7–1.4)

0.8 (0.4–1.4)

1.3 (0.8–2.2)

 Female

17,029

4.0 (2.6–6.1)

0.8 (0.5–1.3)

1.2 (0.7–2.1)

0.6 (0.3–1.0)

1.2 (0.7–2.0)

P

 

0.308

0.967

0.096

0.194

0.459

Age (years)

 35–44

6849

1.9 (1.1–3.2)

0.7 (0.3–1.5)

0.4 (0.2–0.7)

0.4 (0.2–0.7)

0.3 (0.1–0.8)

 45–54

7406

2.1 (1.4–3.0)

0.5 (0.3–1.0)

0.7 (0.5–1.0)

0.3 (0.1–0.8)

0.4 (0.3–0.8)

 55–64

6765

4.5 (3.0–6.8)

0.7 (0.4–1.2)

1.5 (0.9–2.4)

0.5 (0.3–1.0)

1.4 (0.8–2.6)

 65–74

6406

7.6 (5.1–11.2)

1.4 (0.7–2.5)

2.1 (1.3–3.3)

1.5 (0.8–2.8)

3.1 (1.7–5.7)

 75-

4073

15.9 (10.3–23.7)

2.1 (1.1–3.8)

5.2 (3.2–8.3)

3.4 (1.7–6.7)

7.1 (4.0–12.3)

P

 

< 0.001

0.002

< 0.001

< 0.001

< 0.001

BMI (Kg/m2)

 < 18.5

1319

6.2 (3.7–10.4)

1.6 (0.6–4.7)

1.7 (0.6–4.4)

0.7 (0.2–1.8)

3.1 (1.6–6.1)

 18.5–23.9

13,036

4.0 (2.6–6.0)

0.7 (0.4–1.4)

1.2 (0.8–1.8)

0.7 (0.3–1.3)

1.2 (0.6–2.1)

 24–27.9

12,042

3.7 (2.4–5.5)

0.8 (0.5–1.3)

1.1 (0.6–1.9)

0.7 (0.4–1.1)

1.2 (0.7–1.9)

 28-

5102

3.1 (1.9–5.0)

0.9 (0.5–1.5)

0.9 (0.5–1.5)

0.6 (0.3–1.4)

1.1 (0.6–2.0)

P

 

0.042

0.286

0.583

0.996

0.001

Region

 East

14,009

4.2 (2.5–7.1)

0.9 (0.5–1.8)

1.0 (0.6–1.5)

0.8 (0.4–1.6)

1.8 (1.0–3.3)

 Central

11,895

2.4 (1.0–5.9)

0.4 (0.1–0.9)

1.1 (0.4–2.9)

0.2 (0.1–0.6)

0.6 (0.2–2.1)

 West

5595

5.2 (2.8–9.5)

1.2 (0.4–4.3)

1.4 (0.5–3.9)

1.1 (0.3–3.5)

1.1 (0.6–2.0)

P

 

0.134

0.070

0.800

0.022

0.022

Residence

 Rural

15,009

4.5 (2.5–7.9)

0.9 (0.4–1.9)

1.3 (0.7–2.4)

0.8 (0.4–1.6)

1.4 (0.7–2.9)

 Urban

16,490

3.4 (2.0–5.6)

0.7 (0.4–1.5)

1.0 (0.6–1.7)

0.6 (0.3–1.3)

1.1 (0.5–2.3)

P

 

0.407

0.636

0.551

0.603

0.629

Hypertension

 No

18,163

2.8 (1.9–4.2)

0.6 (0.4–1.1)

0.8 (0.5–1.3)

0.4 (0.2–0.6)

0.7 (0.4–1.2)

 Yes

13,336

5.6 (3.8–8.3)

1.1 (0.7–1.8)

1.6 (1.0–2.4)

1.2 (0.6–2.3)

2.2 (1.3–3.6)

P

 

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

Dyslipidemia

 No

21,830

4.0 (2.7–5.9)

0.8 (0.5–1.4)

1.1 (0.8–1.7)

0.7 (0.4–1.1)

1.3 (0.8–2.2)

 Yes

9669

3.4 (2.2–5.1)

0.7 (0.4–1.3)

1.0 (0.6–1.8)

0.6 (0.3–1.2)

1.0 (0.6–1.8)

P

 

0.015

0.700

0.549

0.791

0.025

Diabetes

 No

28,214

3.8 (2.6–5.6)

0.8 (0.5–1.3)

1.1 (0.7–1.6)

0.6 (0.4–1.0)

1.2 (0.7–2.1)

 Yes

3285

4.0 (2.5–6.3)

1.0 (0.6–1.9)

1.5 (0.8–2.9)

1.2 (0.5–2.6)

1.3 (0.7–2.2)

P

 

0.581

0.310

0.131

0.018

0.889

Stroke

 No

30,656

3.7 (2.5–5.5)

0.8 (0.5–1.3)

1.1 (0.7–1.7)

0.6 (0.4–1.1)

1.2 (0.7–2.0)

 Yes

843

7.9 (4.0–15.1)

1.3 (0.4–3.8)

1.9 (0.8–4.7)

1.8 (0.7–4.6)

4.1 (2.2–7.8)

P

 

0.004

0.295

0.185

0.003

< 0.001

CKD

 No

29,453

3.5 (2.4–5.2)

0.7 (0.4–1.2)

1.0 (0.7–1.5)

0.6 (0.4–1.0)

1.1 (0.7–1.9)

 Yes

2046

9.2 (6.0–13.9)

2.3 (1.3–4.0)

3.0 (1.7–5.1)

1.6 (0.7–3.5)

3.2 (1.5–6.5)

P

 

< 0.001

< 0.001

< 0.001

0.001

< 0.001

  1. Data were represented as a percentage (95% CI)
  2. All values were weighted to represent the total population of Chinese aged 35 years or older based on the Chinese census 2010
  3. VHD, valvular heart disease; MS, mitral stenosis; MR, mitral regurgitation; AS, aortic stenosis; AR, aortic regurgitation; BMI, body mass index; CKD, chronic kidney disease
  4. P value for x2 or Fisher’s exact test to assess the difference of prevalence among subgroups according to the characteristics